EXPORT Study First Report - Clinical Trial Results：出口研究的首次报告临床试验的结果.pptVIP

下载本文档

6
0
约1.19万字
约 30页
2018-06-23 发布于浙江
举报
版权申诉

EXPORT Study First Report - Clinical Trial Results：出口研究的首次报告临床试验的结果.ppt

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

EXPORT Study First Report - Clinical Trial Results：出口研究的首次报告临床试验的结果

EXPORT STUDYFirst Report TCT 2007 Bernard Chevalier, Keyur Parikh, Martine Gilard, Irene Lang On behalf of the study investigators EXPORT Study To evaluate flow improvement in patients with Acute Myocardial Infarction undergoing either conventional stenting or a strategy of primary aspiration followed by stenting using the ExPORT? Aspiration Catheter in patients presenting with Acute Myocardial Infarction EXPORT Study CE Mark and FDA approved device, with the following indication for use in central and peripheral circulatory system: Contain and aspirate embolic material (thrombus/debris) while performing transluminal angioplasty or stenting procedures To sub selectively infuse/deliver diagnostic or therapeutic fluids. Background Hypothesis: if a technique reduces by 33% the risk of no-reperfusion (basis: Claeys et al.) Hard endpoint: mortality 6.7% versus 5.1% …7056 patients Background Background Background Background Blush 0 No appearance of blush or opacification of the myocardium Blush 1 Presence of blush but no clearance of contrast (stain is present on the next injection) Blush 2 Blush clears slowly – clears minimally or not at all during three cardiac cycles Blush 3 Blush begins to washout and is only minimally persistent after three cardiac cycles Background Background EXPORT Study EXPORT Study EXPORT Study Main Inclusion Criteria ST-segment elevation of ? 2 mm in ? 2 contiguous leads De novo lesions in mid or proximal segments of native coronary vessels A visual estimated reference vessel diameter ? 2.5 mm TIMI flow of 0 or 1 before wiring Main Exclusion Criteria Pre-cathlab use of lytic therapy or IIb/IIIa antagonist Patients presenting with a cardiogenic shock (blood pressure 90 mmHg) Patients presenting with cardiac arrest at any time before intervention Patients previously treated with a pacemaker or with left/right bundle branch block Any planned use of distal protection device Multivessel coronary artery disease with planned non-target artery PCI o