Agents Used in the Treatment of Skin Disorders：用于治疗皮肤病的药物.pptVIP

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2018-06-23 发布于浙江
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Agents Used in the Treatment of Skin Disorders：用于治疗皮肤病的药物.ppt

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Agents Used in the Treatment of Skin Disorders：用于治疗皮肤病的药物

* * * * * * * * Anti-Inflammatory Agents Effectiveness depends on potency of drug, vehicle used, skin thickness and integrity, and presence of moisture Damaged skin may increase amount of drug absorbed systemically Anti-Inflammatory Agents Increases systemic side effects Occlusive dressings increase absorption Potent agents must be used with caution on thin skin Do not use in the presence of fungal infection * * Antiparasitic Agents Parasites live on outer surfaces Lice and scabies Lice is transmitted person to person Lives on head, body, or pubic area Scabies is a mite; burrows under the skin and lays eggs Drug of choice is lindane Do not use in children under 2 Can cause seizures if applied to open skin CNS toxicity * Additional Dermatologic Agents Debriding agents Antineoplastic agents Burn treatment agents Eczema agents Psoriasis agents Topical hair agents Agents for diabetic foot ulcer * Diabetic Foot Ulcers Leading cause of amputations Microvascular and neurological changes due to long-term elevated blood sugar levels Increases migration of cells responsible for wound healing to site of ulcer Diabetic Foot Ulcers Needs adequate blood supply Gel form helpful for protecting healing wounds Long-term therapy required – Regranex promotes healing * * Antineoplastic Agents Destroys cells that grow rapidly Topical treatment of solar or actinic keratosis Premalignant skin lesions Develops in fair skinned people exposed to heavy sunlight Also used to treat basal cell carcinomas Antineoplastic Agents Use nonmetallic applicators Protect skin with rubber gloves Wash hands immediately Avoid contact with eyes, nose, or mouth Avoid exposure to sunlight * * Agents Used to Treat Burns Treatment aimed at preventing infection Important to prevent toxic absorption into systemic circulation Blood supply is impaired Topical products may be only way to prevent infection Agents used to treat burns Occludes site to prevent contamination Applied to burn after cleaning and debriding