13-2 流感大流行快速围堵（英文）.ppt

World Health Organization Rapid Containment:Rationale and Key Concepts Dr CK Lee (利千基) Communicable Disease Surveillance Response Team WHO China Email: leec@ September 2007 Containment: Concept Aims to stop the development of pandemic influenza when it is initially detected and before the virus has been able to spread more widely one of the five major strategic actions that form the basis of the WHO strategic action plan for pandemic influenza Phase-wise intervention Containment: Definitions Containment: Attempt to stop further spread of an emerging pandemic virus Isolation: Separation and restricted movement of sick persons Quarantine: Separation and restricted movement of well persons exposed or presumed exposed Restricted movement: Voluntary or compulsory limitation of movement Social distancing: Measures intended to minimize social interactions Response Versus Containment Rapid response = ROUTINE Early detection of human cases Initial field investigation Standard control measures Notification of national authorities and WHO Rapid containment = EXTRAORDINARY Joint risk assessment by country and WHO Additional field assessment if needed Decision made by national authorities in consultation with WHO Large scale use of antivirals and non-pharmaceutical interventions Rapid Containment: Decision making super-imposed on continuum of response Containment: Probability of Success?  Containment strategy untested; success not guaranteed Probability of success Emergence will be geographically circumscribed Initial clusters will be rapidly detected and reported Antivirals will be rapidly mobilized and administered Population movement will be restricted Given theoretical window and potential impact of pandemic, moral obligation to try Even failed or partially successful containment may slow early spread of the virus. Necessary steps for rapid response to event with pandemic potential Early detection, reporting response Contain