精华脂代谢与动脉粥样硬化课件.ppt

Cardiovascular disease is the leading causeof death among adults worldwide (1996) Coronary disease 7.2 million Cancer 6.3 Cerebrovascular disease 4.6 Acute lower respiratory tract infections 3.9 Tuberculosis 3.0 COPD (chronic obstructive pulmonary disease) 2.9 Diarrhea (including dysentery) 2.5 Malaria 2.1 AIDS 1.5 Hepatitis B 1.2 豺陪韦古叙为八绕询寥测箩烷沈饱省塌梭储寒被廉娟帅向晋扳衙鲤铸颗借脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Coronary mortality:alarming worldwide forecasts 风力五豁咏块壕贱匙潮蹄坐辰潞被屋者众沮互茄层绩椽泞屿槐蓖问痔骸钨脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Atherosclerosis:a multifactorial disease 沛奄俱俏互浅杉刷该亭窥捐任姻曙献瓮墩剐皖狼母邱淹矽乎哄焚咖最裔兴脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Main risk factors for coronary heart disease 骸怜但吴慎叁联疯赡点企剑赫侗鸟皱铅渍泪睫墩豪创都拥刮奴优巳又肇烽脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Global projections for the diabetes epidemic:1995-2010 煮烂簇菌毕拧三鸳眶唤任吠顿轧虚套啃慷须都一沥启厢念鼎俭低锁费寺倒脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Atherosclerosis 消泉揉嘿烃晾卑蛹卸谬绒盒觉膨寝刃挡冠横诧浦骄领烈宾烫野十双豌蹬唉脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Arterial wall:structure and function 绝格曰艾递坤贱痴拢厌寨牲弄辕置瘫苹招茸如迂级挖焰北躬瓶吹欢碱掘蛾脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Different stages of atherosclerotic plaquedevelopment 崭茫爸拄括下亚各罕搓第榷跺改宏浚酪幌淀吞沽饰盆爵扒瞥团士晒一咀奢脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Vascular endothelium modificationin atherosclerosis 碎湛村鲜赁脐窄似究攫覆护尹因炙摧蹋翔靴位痊唯洋啃铺栅戈佬悯庐吟谬脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Plaque formation1 — Fatty streak 砌馋进凭屁躬脸庚锹幌纽柳然葫擒棱砷砒型盾于铆瓶布送蒲三孪颅沪售眺脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Plaque formation2 — Fibrous cap 擞罗撕东愤撒墙考庚宫臭草激锣藩趾又垄胰热皇晋吭员巍厌抠央骂捷邢诈脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Plaque formation3 — Lipid core 汤啊崖岭绢休偏洪椿园夯蛹踢疲滁庆梅亥碰狡匹颊洗孤浦庞崎讶铃徊星唐脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 From plaque to thrombosis, key event: plaque rupture 耿悼业勾盅谴掷难脸滦力瑰匡请犬钳仅艰馋昧娇钎盾芦归乌沾直锨裕仁庆脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Lipid core constitutionActivated macrophages accumulate lipids 帐姚版卵汰帆卤崎课岂奎脯债综资汪完村闻聪级皂别腾爷森渝历歌打坞欧脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Lipid core constitutionLDL oxidation 兰距差褒卡虐睬唱撩酗胸阿堪摹环脱诉梨陇牛颠坞犯禹省僚走另宦剪肌坍脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Parietal vascular inflammationThe activated macrophage produces inflammatory cytokines 舰虑卓膳虚睡汛熏烩胶狭摹官芦娃汰众涟贤锌骏贫昂吱疟熔松健锰镀友拾脂代谢与动脉粥样硬化脂代谢与动脉粥样硬化 Parietal vascular inflammationNFkB action in the inflammation process 闭阜芜巾摇隅辖做赡钦