灯盏花素分散片制工艺研究.docVIP

灯盏花素分散片制备工艺研究 摘要：目的：制备灯盏花素分散片，确定工艺流程。方法：以崩解时限和片剂硬度为指标，采用单因素考察和实验对分散片处方进行筛选、优化。按优处方制备的可在3 min内完全崩解并且全部通过2号筛,符合《中国药典》对分散片的要求其体外溶出度明显优于普通片。该工艺可操作性强、重现性好能适工业大生产的要求Preparation Technique of Breviscapinum Dispersible Tablets ABSTRACT：AIM： To establish the preparation techn of Breviscapinum dispersible tablets. METHODS：The preparat process was scanned out by single factor test and orthogonal design．A comprehensive scoring analysis was performed with disintegrating time and rigidity as the indexes. RESULTS：The optimized formulation of Breviscapinum dispersible tablets could be totally disintegrated w