不同强度跑台运动抗糖尿病作用及其机制分析-anti-diabetes effect of different intensity treadmill exercise and its mechanism analysis.docxVIP

insulin(Ins)levelshigherthantheDSLgroupand,withsignificantdifferences(P0.05),DSHishigherthanthelevelofInsGroupDSLGroup,DSMGroupInslevelhigherthantheDSHgroup,butnotwithdifferences(P0.05);DSMgroupandtheDSHgroupofβ-cellfunctionindex(HBCI)aresignificantlyhigherthantheDSLgroup,haveaverysignificantdifference(P0.01),DSMGroupHBCIthanDSHgroup,thereisnodifference(P0.05);intriglyceride(TC),cholesterol(TG),lowdensitylipoprotein(LDL-C)onthecomparison,DSMgroupminimum,DSHGroupfollowed,DSLgroupthehighest,andtheydonothavedifferences(P0.05),highdensitylipoprotein(HDL-C)DSMhighest,thanDSHGroupfollowed,DSLgroupthelowest,andnotstatisticallysignificant(P0.05);atglycosylatedserumprotein(GSP),serumNOlevelandNOSonthecomparison,DSMgrouphavelessthantheDSLgroup,significantdifferences(P0.05),DSMgroupthaninDSHgroup,DSHgroupthaninDSLgroupdifferencesdidnotexist(P0.05).Conclusion:(1)ThroughWisterrats50mg/kgtwicebytailveininjectionofalloxan,successfulsetupadiabeticratmodel(modelasuccessrateof59%)fordiabetesresearchlaboratorypremiseconditions.(2)low,middleandhighthreedifferentintensitytreadmillexerciseondiseasepreventionandtreatmentofdiabeticratshaveanactiverole.(3)medium-intensitytreadmillexercise(27m/min)ofdiabeticratsbloodglucose,bloodlipids,loweringofglycosylatedserumproteinandseruminsulinlevels,isletβ-cellfunctionimprovetheeffectofthemostobvious,issuperiortolow,high-intensityexercise.Keywords:intensity;exercisesintreadmill;bloodglucose;diabeticrats;meghanism缩略词DM(DiabetesMellitus)糖尿病T2DM(Type2DiabetesMellitus)2型糖尿病FPG(FastingPlasmaGlucose)空腹血糖值Ins(Insulin)胰岛素IR(InsulinResistance)胰岛素抵抗ISI(InsulinSensitivityIndex)胰岛素敏感指数HBCI(HomeostasisBetaCellIndex）胰岛B细胞功能指数GLUT4(GlucoseTransporter4)葡萄糖运载蛋白4GSP(Glycosylatedserumprotein)糖化血清蛋白TG(Triglyceride)甘油三酯TC(TotalCholesterol)总胆固醇LDL(Low-DensityLipoprotein)低密度脂蛋白HDL(High-DensityLipoprotein)高密度脂蛋白NO(NitricOxide)一氧化氮NOS(NitricOxideSynthase)一氧化氮合酶学位论文独创性声明本人郑重声明：所提交的学位论文是本人在导师的指导下，独立进行研究工作所取得的成果。尽我所知，除文中已经注明引用的内容外，本论文不含其他个人或集体已经发表或撰写过的研究成果，也不含为获得西北师范大学或其他教育机构的学