磁共振波谱对前列腺疾病的诊断价值及其与病理对照分析-diagnostic value of magnetic resonance spectroscopy in prostate diseases and its comparison with pathology.docxVIP

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磁共振波谱对前列腺疾病的诊断价值及其与病理对照分析-diagnostic value of magnetic resonance spectroscopy in prostate diseases and its comparison with pathology.docx

磁共振波谱对前列腺疾病的诊断价值及其与病理对照分析-diagnostic value of magnetic resonance spectroscopy in prostate diseases and its comparison with pathology

7772%、88%、77%), MRS had better diagnostic value, especially combined the threetechniques, the sensitivity, specificity, positive predict value, negative predict value and accuracy for the diagnosis of PZPC cound get to 96%、80%、84%、95%及 87%.3、Positive correlation was found between the (Cho + Cr) / Ci value and clinic staging(r=0.542,P=0.003)and gleason score(r=0.651,P=0.000).4、difference was found between prostate cancer and BPH in MVD (P=0.004)and VEGF(P=0.005). The study indicates that MVD 、VEGF 、Ki-67 and cellular density are closely related with the (Cho + Cr) / Ci value .Conclusion1、MRS with only external-body surface coil at 3.0T can be used to evaluate the metabolic level of prostate, especialty combined other MR techniques, it canobvious improve the diagnosis of prostate diseases.2、 MRS can be used to evaluate the proliferation and angiogenesis of prostate cancer Key words magnetic resonance spectroscopy; external-body surface coil cellular density microvascular density vascular endothelial growth factor Ki-6733英 汉 缩 略 词 表英文缩写 英文全称 中文译名MRI MRS DWI TRUS PSA BPHROIMagnetic Resonance Imaging Magnetic Resonance Spectroscopy Diffusion Weighted Imaging transrectal ultrasoundprostate-specific antigen benign prostatic hyperplasiaregions of interest磁共振成像磁共振波谱 扩散加权成像 经直肠超声 前列腺特异性抗原 良性前列腺增生 感兴趣区FOVfield of view视野TRtime of repetition重复时间TET2WItime of echoT2-weighted Imaging回波时间T2 加权成像PRESS STEAMCr Cho Ci MVDVEGFpoint-resolved echo spin spect roscopy stimulated echo acquisition mode creatinecholine citralmicrovascular densityvascular endothelial growth factor点分辨自旋回波波谱激励回波采集模式 肌酸胆碱 枸橼酸 微血管密度血管内皮生长因子11学位论文原创性声明和版权使用授权书学位论文原创性声明本人郑重声明:所呈交的学位论文,是本人在导师的指导下,独立进行研究工作所取得 的真实成果。除文中已注明引用的内容外,本论文不含任何其他个人或集体已经发表或撰写 过的作品成果。对本论文的研究做出重要贡献的个人和集体,均已在文中以明确方式标明。 本人完全意识到本声明的法律结果由本人承担。作者签名(手写): 导师签名(手写): 年 月 日 年 月 日学位论文版权使用授权书本学位论文作者完全了解学校有关保留、使用学位论文的规定,同意学校保留并向国家有关部门或机构(如国家图书馆、中国学术期刊电子杂志社的《中国 优秀博硕士学位论文数据库》、中国科学技术信息研究所的《中国学位论文全文 数据库》等)送交论文的复印件和电子版,允许论文被查阅和借阅。本人授权福 建医科大学可以将本学位论文

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