青岛大学基础医学院医学免疫学课件 chapter10.ppt

Chapter 10 The cells of adaptive immune response：T lymphocytes Immune response： Innate immune response——MPS, DC, NK, NKT, ??T, B1 cells etc. Adaptive immune response——T、B cells T cells： Origin——bone marrow:multiple hematopoietic stem cell → lymphoid progenitor Development——thymus Function——cellular immune response and humoral immune response Section 1 Membranous molecules on T lymphocytes and their functions 一、TCR-CD3 complex 1、The structure and function of TCR TCR——T细胞抗原受体（T cell antigen receptor） 为所有T细胞表面的特征性标志，以非共价 键与CD3分子结合，形成TCR-CD3 complex Structure——heterogenous dimer，每条肽链均为跨膜