§9 Carbohydrates glycobiology.ppt

liguofu in cell surface in cell surface Proteoglycans are in cell surface extracellular matrix Glycoproteins in cell surface Glycolipids are membrane components Function of oligosaccharide in biological processes §9.3 Glycoconjugates Proteoglycans are in cell surface extracellular matrix Glycoproteins in cell surface Glycolipids are membrane components Function of oligosaccharide in biological processes §9.3 Glycoconjugates Proteoglycans are in cell surface extracellular matrix Glycoproteins in cell surface Glycolipids are membrane components Function of oligosaccharide in biological processes §9.3 Glycoconjugates Structures of A, B, and O antigens One of the roles of oligosaccharide in cell surface §9.1 Mono- Disaccharides §9.2 Polysaccharides (Glycans) §9.3 Glycoconjugates §9.4 Analysis of Carbonhydrates §9 Carbonhydrates Glycobiology The End * §9.1 Mono- Disaccharides §9.2 Polysaccharides (Glycans) §9.3 Glycoconjugates §9.4 Analysis of Carbonhydrates §9 Carbonhydrates Glycobiology §9.1 Mono- Disaccharides Monosaccharides Derivatives of Monosaccharides Disaccharides Monosaccharides Monosaccharides are Aldehydes or ketones with one or more hydroxyl groups. Monosaccharides in life are D form. D-glyceraldehyde L-glyceraldehyde Enantiomers Monosaccharides (cntd) Monosaccharides Aldoses Aldotrioses Aldotetroses Aldopentoses Aldohexoses Aldoheptoses Ketoses Ketotrioses Ketotetroses Ketopentoses Ketohexoses Ketoheptoses Aldehydes or ketones with one or more hydroxyl groups. liguofu Monosaccharides (cntd) 赤藓糖 苏阿糖 阿拉伯糖 核糖 木糖 来苏糖 阿洛糖 阿卓糖 葡萄糖 甘露糖 古洛糖 艾杜糖 半乳糖 塔罗糖 Num. of steroisomers = 2n n = Number of chiral C 醛糖 liguofu Monosaccharides (cntd) Num. of steroisomers = 2n n = Number of chiral C 酮糖 二羟丙酮 赤藓酮糖 核酮糖 木酮糖 阿洛酮糖 果糖 山梨糖 塔格糖 Monosaccharides (cntd) Anomeric carbon Anomers 形成分子内半缩醛 (hemiacetals) Monosaccharides (cntd) 形成分子内半缩酮 (hemiketals) Haworth perspective formulas Monosaccharides (cntd) Monosaccharides (cntd) b-D-glucopyranose. b-D-ribose Derivatives of Mon