慢性心力衰竭是内科常见的进展性危重症，是大多数器质性心脏病的终末.docVIP

温阳活血利水方对慢性心衰患者利钠肽前体及生活质量影响的临床研究*沈安明 谢轶群 吕军 李晓丽 王丽晓 唐海军 徐蕾蕾 浦强（江苏省如皋市中医院 如皋226500）摘要：目的：观察温阳活血利水方对慢性心力衰竭的临床疗效。方法：将60例慢性心力衰竭患者随机分为治疗组与对照组，每组30例，两组均应用慢性收缩性心力衰竭的标准治疗方案，治疗组在此基础上加服温阳活血利水方，观察时间为2周。比较两组症状体征量化积分、生活质量评分、临床疗效、左心室射血分数、6 min步行试验、血浆N-末端 HYPERLINK /grid2008/brief/detailj.aspx?dbCode=index=QueryID=4CurRec=7 \t NewBriefDetail B型利钠肽前体。结果：两组治疗前后症状体征量化积分、生活质量评分比较均有明显改善，差异有统计学意义（P＜0.05）。治疗后治疗组症状体征量化积分、生活质量评分均低于对照组，差异有统计学意义（P＜0.05）。治疗组总有效率为66.7%，对照组总有效率为46.7%，差异有统计学意义（P＜0.05）。两组治疗前后左心室射血分数、6 min步行试验、血浆N-末端 HYPERLINK /grid2008/brief/detailj.aspx?dbCode=index=QueryID=4CurRec=7 \t NewBriefDetail B型利钠肽前体均有明显改善，差异有统计学意义（P＜0.01）。治疗后治疗组左心室射血分数、6 min步行试验、血浆N-末端 HYPERLINK /grid2008/brief/detailj.aspx?dbCode=index=QueryID=4CurRec=7 \t NewBriefDetail B型利钠肽前体均优于对照组，差异有统计学意义（P＜0.05）。治疗期间两组均无不良反应发生。结论：温阳活血利水方治疗慢性心力衰竭安全有效。关键词：慢性收缩性心力衰竭；温阳活血利水方；利钠肽前体；疗效Clinical Research on the Effect of Wenyanghuoxuelishui Decoction on NT-proBNP and the Quality of Life in Patients with Chronic Heart FailureSHEN An-ming, XIE Yi-qun, LV Jun(Department of Heart Disease, Rugao Hospital of Traditional Chinese Medicine, JiangsuAbstract: Objective: To observe the clinical effect of Wenyanghuoxuelishui decoction treatment of chronic heart failure. Methods: 60 Patients with chronic heart failure were randomly divided into treatment group and control group, 30 cases for each group. Both groups treated with the standard treatment of chronic heart failure. The treatment group was treated with Wenyanghuoxuelishui decoction at the same time. Observation time was 2 weeks. The changes of signs and symptoms, quality of life (QOL) score, plasma N-terminal pro B-type natriuretic peptide (NT-proBNP), left ventricular ejection fraction (LVEF), the 6-minute walk test (6-MWT) and comprehensive efficacy were compared between two groups. Result: There were significant differences in scores of symptoms and scores of QOL between the two groups before and after treatment (P＜0.05). The scores of signs and sy