【持续性肾脏替代治疗CRRT英文ppt课件】Continuous Renal Replacement Therapy(51p).pptVIP

Continuous Renal Replacement Therapy;Content;PHYSICAL PRINCIPLES DEFINITIONS;30 000 Da;30 000 Da;30 000 Da;30 000 Da;30 000 Da;30 000 Da;30 000 Da;30 000 Da;30 000 Da;DEFINITIONSBELLOMO et al. Am J Kidney Dis, 28, (Suppl 3) 1996; SCUFSlow Continuous Ultrafiltration; CVVHContinuous Veno-Venous Hemofiltration; CVVHDContinuous Veno-Venous Hemodialysis ; CVVHDFContinuous Veno-Venous Hemodiafiltration ;EFFICIENCY;CLINICAL ISSUES;CLINICAL INDICATIONS;CRRT AND INFLAMMATIONSepsis an example;HYPOTHESIS FOR MODS PREVENTION;CAVH after Staph Aureus in swine(Lee PA et al; Crit Care Med 1993; 21: 914-924);CAVH after Staph Aureus in swine(Lee PA et al; Crit Care Med 1993; 21: 914-924);EDTX HEMOFILTRATION :In vivo experimental studies (1);EDTX HEMOFILTRATION :In vivo experimental studies (2);EDTX HEMOFILTRATION :In vivo experimental studies;From Mateo et al AJRCCM 1996 (Abst);From Mateo et al AJRCCM 1996 (Abst);From Mateo et al AJ RCCM 1996 (Abst); CLP model of acute peritonitis in pig 24 hrs of CAVH vs no CAVH ex vivo test of PMN phagocytosis for Candida (T0, T24, 48, 72H) hemodynamic, gazometric biologic data ;CAVH ATTENUATES PMN PHAGOCYTOSIS IN PORCINE MODEL OF PERITONITIS (A. DiScipio et al, Am J Surg. 173; 1997);Extensive activation of inflammatory responses;CONVECTIVE ELIMINATION OF CYTOKINES;CONVECTIVE ELIMINATION OF CYTOKINES;Elimination of inflammatory mediators by hemofiltration;High volume HF in severe sepsis(P Honoré et al . Hop St Pierre) (in press CCM);Adequate biocompatibility blood - membrane interaction induction of chronic inflammatory reaction Substrate losses (glucose, amino-acids, ...) Hormones losses Heat loss Catheter-associated complications/infections Costs Need for prolonged anticoagulation coating systems;CONTROL STUDIES;PERSPECTIVES;Facteur Dépresseur MyocardiqueLultrafiltrat des animaux septiques provoque :;Systemic reaction;Hemodiafiltration The use of hemodialysis, hemofiltration and ultrafiltration;Dialysis The u