形态实验学消化道寄生吸虫与线虫.pptVIP

形态实验学：消化道与疾病－寄生虫学部分消化道寄生线虫消化道寄生吸虫 南京医科大学病原生物学系 Ascaris lumbricoides Life-cycle 雄蛔虫交合刺 成虫 雌雄异体 雌虫：长20-35cm，有的可达49cm，生殖系统为双管型，阴门位于虫体腹中部之前 雄虫：15-31cm，尾部向腹面弯曲，生殖系统为单 管型，镰刀状交合刺一对 An adult Ascaris worm(female) 受精蛔虫卵 Fertilized Ascaris lumbricoides egg(still at the unicellular stage) 平均大小60×45μm 宽椭圆形 棕黄色 卵壳较厚，自外向内分三层：受精膜（卵黄膜）、壳质层和蛔甙层。壳外有一层蛋白质膜，凹凸不平，被胆汁染成棕黄色 内含一大而圆的受精卵细胞，受精卵细胞与卵壳间有新月形空隙 未受精蛔虫卵Unfertilized Ascaris lumbricoides egg 大小90×40μm 长椭圆形 棕黄色 壳质层与蛋白质膜均较薄，无蛔甙层 内含许多大小不等的折光性颗粒 两种蛔虫卵比较 Three fertilized eggs (one decorticated, on the right) of Ascaris lumbricoides Ascaris lumbricoides egg containing a larva(infective if ingested) Ascaris lumbricoides larva hatching from an egg 鞭虫(Trichuris trichiura)(Whipworm) Adult worms look like whips Light infestations are frequently asymptomatic Heavy infestations may have bloody diarrhea Long-standing blood loss may lead to iron-deficiency anemia Rectal prolapse is possible in severe cases. Trichuris trichiura Life-cycle Trichuris trichiura adult worm Trichuris trichiura adult worm in intestine 虫卵? Trichuris trichiura eggs Enterobius vermicularis Enterobius vermicularis Life-cycle Enterobius vermicularis adult worm 虫 卵 55×25μm 一则较平，一则稍凸，柿核状 无色透明 卵壳厚 卵内含一蝌蚪期幼虫 Enterobius vermicularis eggs 钩虫(Hookworm) 钩虫(Hookworm) Two species of hookworms commonly infect humans, Ancylostoma duodenale and Necator americanus The most significant risk of hookworm infection is anemia Hookworm Life-cycle 钩虫成虫 约1cm，肉红色，死后为灰白色。其前端较细，有一口囊，是附着于宿主肠壁的器官。 十二指肠钩虫有两对钩齿 美洲钩虫 有一对板齿 Adult worm of Ancylostoma duodenale.? Anterior end is depicted showing cutting teeth. copulatory bursa of a male Ancylostoma duodenale showing the two separate spicules copulatory bursa of a male Necator americanus showing the two spicules not well separated 二种钩虫成虫形态主要鉴别点 虫卵 60×40μm 椭圆形 壳薄，无色透明 卵内多为2-4个卵细胞，卵壳与卵细胞间有明显空隙 二种钩虫卵不易区别 Eggs of Ancylostoma duodenale and Necator americanus cannot be distinguished morphologically Hookworm rhabditiform larva Hoo