Illness Evaluation CDC Emergency Preparedness 出疹性疾病的评价 CDC应急准备ppt课件.pptVIP

Rash Illness Evaluation;Rash Illness Evaluation;Need for a Diagnostic Algorithm?;Need for a Diagnostic Algorithm?;~1.0 million cases varicella (U.S.) this year and millions of cases of other rash illnesses If 1/1000 varicella cases is misdiagnosed?1000 false alarms Need strategy with high specificity to detect the first case of smallpox Need strategy to minimize laboratory testing for smallpox (risk of false positives);Assumptions/Limitations;Smallpox Disease;Smallpox Disease;Smallpox: Day 2 of Rash;Smallpox: Day 4 of Rash;Smallpox RashVesicles Pustules;Classic Smallpox Lesions: Pustules;Rash Distribution;Differential Diagnosis;Differentiating Features: Varicella;Differentiating Features: Varicella;Varicella ;Varicella Adult Case;Varicella: Infected Lesions;Differential Diagnosis;Differential Diagnosis;Differential Diagnosis;Goal: Rash Illness Algorithm;Investigation Tools;Investigation Tools;Smallpox SurveillanceClinical Case Definition;Smallpox: Major Criteria;Smallpox: Minor Criteria;Evaluating Patients for Smallpox;Immediate Action for Patient with Generalized Vesicular or Pustular Rash Illness;High Risk: All 3 Major Criteria;Response: High Risk Case;Moderate Risk;Response: Moderate Risk Case;Low Risk;Response: Low Risk Case;Smallpox Pre-event Surveillance;CDC Rash Illness Response Team Experience with Use of Algorithm;CDC Rash Response Team Experience with Use of Algorithm;Experience with Implementation of Rash Algorithm ;CONDITION;Generalized Rashes following Smallpox Vaccination:Generalized Vaccinia;Generalized Rashes following Smallpox Vaccination:Eczema Vaccinatum;Generalized Rashes following Smallpox Vaccination:Eczema Vaccinatum;Laboratory and Pathology Support for Rash Illness Evaluation;Electron microscopy Pox virus Herpes virus Other viruses HSV1 and HSV2 Tzanck smear PCR and culture;Vaccinia PCR (if vaccinated) Other tests as clinically indicated: Syphilis, enterovirus, rickettsia, staph, strep, molluscum contagiosu