胃癌术后临床试验ppt课件.pptVIP

胃癌术后治疗相关临床试验;主要临床试验;NCCN指南;NCCN指南; assigned patients： → perioperative chemotherapy and surgery (250 patients) Chemotherapy ：3*ECF preoperative + 3*ECF postoperative ECF ：epirubicin (50 mg/m2)；cisplatin (60 mg/m2) ；fluorouracil (200 mg/m2) for 21 days. →surgery alone (253 patients). The primary end point was overall survival. --- N Engl J Med. 2006 Jul 6;355(1):11-20.;围手术期化疗-MAGIC试验;术后辅助化疗;术后辅助化疗--ACTS-GC;3y os：80.1% vs 70.1% ;术后辅助化疗--CLASSIC;(520);术后辅助放化疗--INT-0116（SWOG 9008）;OS：36m vs 27m; This update, presents data on failure patterns、second maligna