牙体病学ppt课件龋病病因学.pptVIP

龋 病 病 因 学;研究龋病病因、病理、治疗和预防Cariology is a science for study the etiology、pathology、therapy  and prevention of dental caries.;对龋病的认识;龋病的基本特征;龋 病;龋病的危害;龋 病 的 进 展;牙源性病灶感染;龋病病因学说ETIOLOGY OF DENTAL CARIES;龋病病因的内因学说;虫牙学说 WORMS;磷 酸 盐 学 说PHOSPHATASE THEORY; 糖 原 学 说 GLYCOGEN THEORY;龋病病因的外因学说;化学细菌学说 CHEMICO-BACTERIAL THROEY;化学细菌学说;化学细菌学说的局限性;蛋白溶解学说PROTEOLYSIS THEORY;蛋白溶解学说的局限性;蛋白溶解-螯合学说PROTEOLYSIS-CHELETION THEORY;蛋白溶解-螯合学说的局限性;Orland (1955) Animal Studies;龋病病因的现代学说CURRENT CONCEPTS OF CARIES ETIOLOGY; The four circles represent the parameters involved in the carious process;龋病发生中细菌作用的证据Evidences implicating microorganisms  in the etiology of caries;Oral bacteria can demineralize enamel and dentin in vitro and produce caries-like lesions 从口腔分离出的细菌可引起牙釉质、 牙本质脱矿，产生龋样损害 5. Microorganisms have been histologically demonstrated invading carious enamel and dentin.They can be isolated and cultivated from carious lesions 组织病理学观察在龋损牙釉质、牙本质 内有微生物存在，可以从龋坏中分离和 培养;龋病病因研究史中的重要研究;牙菌斑生物膜的致病性PATHOGENIC POTENTIAL OF DENTAL PLAQUE BIOFILM ;牙菌斑的致病因子PATHOGENIC CONSTITUENTS OF DENTAL PLAQUE; 致炎因子 INFLAMMATION-INDUCING SUBSTANCES chemotactic substances 趋化因子 activators of complement cascade 补体激活因子 histamine 组胺 mitogens 促细胞分裂剂; 引起的间接组织损害 INDIRECT TISSUE DAMAGE BY HOST IMMUNOLOGICAL RESPONSE endotoxin 内毒素 peptidoglycan 肽聚糖 polysaccharides 多糖 bacterial antigens 细菌抗原;龋病微生物学 MICROBIOLOGY OF　DENTAL CARIES;致龋细???的重要特征THE IMPORTANT PROPERTIES ＯＦCARIOGENIC BACTERIA;糖 的 致 龋 作 用Cariogenicity of carbohydrates;CARIES AND DIET 龋病与食物Controlled human studies----Vipeholm 人体对照试验;龋病与食物 CARIES AND DIET Controlled human studies---Hopewood House;易 感 宿 主THE SUSCEPTIBLE H