细胞膜及细胞表面ppt课件.pptVIP

cell-adhesion molecules (CAMs) 细胞黏连分子分成钙黏素，免疫球蛋白超家族，整合素，选择素。 其他参加细胞粘连的膜蛋白 A large number of CAMs fall into four major families: the cadherins, immunoglobulin (Ig) superfamily, integrins, and selectins. Some other membrane proteins, whose structures do not belong to any of the major classes of CAMs, also participate in cell–cell adhesion in various tissues. 相同粘连分子的连接称为同亲性homophilic binding，不同粘连分子连接称为异亲性heterophilic binding 细胞粘连可以是牢固的，如上皮细胞间的连接；也可以是微弱的，短暂的，如免疫细胞穿越血管内皮。 Cell–cell adhesions can be tight and long lasting or relatively weak and transient. The associations between nerve cells in th