香连化浊解毒方对溃疡性结肠炎大鼠结肠组织nf-κb、cox-2 mrna表达影响的实验研究-experimental study on the effect of xianglianhuazhuo jiedu recipe on nf - κ b and cox - 2 mrna expression in colonic tissue of ulcerative colitis rats.docxVIP

下载本文档

6
0
约4.12万字
约 50页
2018-08-10 发布于上海
举报
版权申诉

香连化浊解毒方对溃疡性结肠炎大鼠结肠组织nf-κb、cox-2 mrna表达影响的实验研究-experimental study on the effect of xianglianhuazhuo jiedu recipe on nf - κ b and cox - 2 mrna expression in colonic tissue of ulcerative colitis rats.docx

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

香连化浊解毒方对溃疡性结肠炎大鼠结肠组织nf-κb、cox-2 mrna表达影响的实验研究-experimental study on the effect of xianglianhuazhuo jiedu recipe on nf - κ b and cox - 2 mrna expression in colonic tissue of ulcerative colitis rats

万方数据万方数据目录中文摘要············································································································1 英文摘要············································································································4 英文缩写············································································································8 研究论文香连化浊解毒方对溃疡性结肠炎大鼠结肠组织 NF-κB、 COX-2 mRNA 表达影响的实验研究前言 9 材料与方法······························································································10 结果··········································································································15 附图··········································································································18 附表··········································································································24 讨论··········································································································27 结论··········································································································34 参考文献··································································································35 综述溃疡性结肠炎的中医药研究进展······················································39 致谢··················································································································48 个人简历··········································································································49 中中文摘要 PAGE 10万方数据 PAGE 10 万方数据香连化浊解毒方对溃疡性结肠炎大鼠结肠组织 NF-κB、COX-2 mRNA 表达影响的实验研究摘要目的：本实验研究通过观察香连化浊解毒方对溃疡性结肠炎大鼠模型的一般状况、疾病活动指数评分、结肠黏膜组织病理学改变以及结肠组织中 NF-ΚB、COX-2 mRNA 表达的影响，试图从分子水平探讨该方治疗溃疡性结肠炎的作用机理，为本方在临床应用中提供实验依据。方法：将 60 只健康 Wistar 雄性大鼠（体重 200g-250g）适应性喂养 7 天后，按随机数字表法随机分成 6 组，分别为：正常组（NG），模型组（MG），香连化浊解毒方高剂量组(HDG)、香连化浊解毒方中剂量组(MDG)、香连化浊解毒方低剂量组(LDG)，柳氮磺吡啶组(SASP)，每组 10 只。除 NG 之外，其余的五组大鼠均采用 2,4,6-三硝基苯磺酸(TNBS)／乙醇联合造模法诱导 UC 大鼠模型，造模成功后，各中药治疗组给予相应剂量的中药灌胃，SASP 予柳氮磺吡