原创力文档- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
查看更多
生物化学与分子生物学 PPT素材 可根据需要选择取舍 Embryonic stem cells Egg donor Sperm donor Egg fertilization Culture fertilized cells for several cell divisions Dissociate cell cluster for subculturing and further utilization Freeze in N2 for long-term storage Use for In Vitro fertilization Potential use for therapeutic cloning Tet r Amp r Ori pBR322 4361bp Ori pBluescript II Amp r LacI MCS LacZ f1 Ori Ori pUC18 Amp r MCS LacZ Common Cloning Vectors Ori pCR2.1 3929bp Amp r Kan LacZ f1 Ori M13 (-) APCRA T7 M13 (+) Ori pGEM 11Zf 3221bp Amp r LacZ f1 Ori T7 SfiI-SacI-EcoRI-SalI-Xho-BamHI-ApaI-XbaI-NotI-SphI-NsiI-HindIII SP6 Ori pGEM 9Zf 2912bp Amp r LacZ f1 Ori SP6 NsiI-HindIII-XbaI-EcoRI-SalI-SacI T7 Metabolism of capecitabine 5-FU 5-Fluorouridine 5-FUMP 5-FdUMP Uridine phosphorylase 5-Fluorodeoxyuridine Thymidine phosphorylase Orotate phosphoribosyl transferase Thymidine kinase 5-FUTP 5-FdUTP RNA DNA 5’-nucleotidase 5’-nucleotidase Uridine kinase ATP ADP ATP ADP PRPP Capecitabine Xeloda (prodrug) Carboxyl- esterase 5-Fluoro-5-deoxy cytidine Cytidine deaminase Thymidine phosphorylase 5-Fluoro-5-deoxyuridine Pharmacologically active compound Pertussis toxin NAD ADP Cholera toxin ? ? AC ATP cAMP AC ?S GTP Ligand Pharmacological modulation of cAMP Ligand Ligand Ligand ? ? ?i GDP ?S GDP ? ? ?i GTP ?i GTP NAD ADP Forskolin Rolipram AMP PDE ? ? ?S GTP Mechanism of Penicillin (inhibition of crosslinking peptidoglycan) Tetra- peptide Penta- glycine Glycopeptide transpeptidase Penicillin 40S Inhibition of translation by Rapamycin (Sirolimus) Growth Factor Receptors IP3K PDK PKB mTOR 40S 30S eIF4G eIF4E PABP eIF4A 4E-BP1 eIF4E P P 4E-BP1 P P P P P S6K P P P P P Ribosomal proteins eEF2 eEF2 P P 40S 30S eEF2 kinase CaM eIF2 Rapamycin FKBP-12 TMP Mechanism of 5-fluorouracil (5-FU) deoxyUMP Thymidylate synthase TTP 5-FU Carac, Efudex DNA synthesis 5-Fluorouridine 5-FUMP 5-FdUMP Uridine phosphorylase Uridine kinase 5-Fluorodeoxyuridine Thymidine phosphorylase Orotate phosphoribosyl t
文档评论（0）