108例妊娠合并阴道假丝酵母菌病临床治疗分析.docVIP

108例妊娠合并阴道假丝酵母菌病的临床治疗分析 　　【摘要】目的 探讨108例妊娠合并阴道假丝酵母菌病的治疗方案，总结其疗效及临床价值。方法 选取我院2010年至2011年定期产检的108例患外阴阴道假丝酵母菌病的孕妇，按照临床症状的轻重程度及治疗方案的不同分为轻度症状碳酸氢钠治疗组，采用2%碳酸氢钠溶液阴道擦洗和坐浴；轻度症状硝酸咪康唑治疗组，采用硝酸咪康唑栓阴道用药；重度症状碳酸氢钠治疗，无效再用硝酸咪康唑治疗组，采用2%碳酸氢钠溶液阴道擦洗和坐浴，治疗效果不明显时改用硝酸咪康唑治疗；重度症状硝酸咪康唑治疗组，采用硝酸咪康唑栓阴道用药。治疗1至2周随访，观察其微生物学指标，分析治疗效果，记录相关数据，进行统计分析。结果 用药后一周，轻度症状的两组总有效率对比，无明显差异(P0.05)；重度症状两组总有效率对比，差异显著(P0.05)；治疗后第二周，轻度症状两组、重度症状两组之间的带菌率对比差异显著(P0.05)，具有统计学意义。结论 轻度外阴阴道假丝酵母菌病可单用2%碳酸氢钠溶液阴道擦洗和坐浴治疗，重度外阴阴道假丝酵母菌病可先用2%碳酸氢钠溶液阴道擦洗和坐浴治疗，若效果不明显,再予以硝酸咪康唑栓治疗，此方案具有操作简便、安全性高、经济成本低的优点，具有重要的临床价值。 　　【关键词】妊娠合并阴道假丝酵母菌病 治疗方案 临床价值 　　中图分类号：R714.25 文献标识码：A 文章编号：1005-0515（2011）7-033-02 　　108 cases of pregnant women with vaginal Candida clinical analysis of disease 　　【Abstract】ObjectiveTo investigate 108 cases of pregnant women with vaginal Candida disease treatment programs to summarize the efficacy and clinical value. Methods Our hospital from 2010 to 2011 on a regular basis for check of 108 patients suffering from vaginal Candida disease in pregnant women, according to the severity of clinical symptoms and treatment options were divided into mild symptoms of sodium bicarbonate treatment group, using 2 % sodium bicarbonate solution, scrub and bath vagina; miconazole nitrate treatment group with mild symptoms, the use of miconazole nitrate vaginal suppository medication; severe symptoms of sodium bicarbonate treatment, ineffective treatment miconazole nitrate group and then, with 2% bicarbonate sodium vaginal scrub and bath, treatment was not obvious when the switch miconazole nitrate treatment; severe symptoms of miconazole nitrate treatment group, the use of miconazole nitrate vaginal suppository medication. Treatment of 1-2 weeks follow-up, observe the microbiological indicators, analyzes the treatment effects, record data, for statistical analysis. Results After a week with mild symptoms of total effective contrast, no significant difference (P 0.05); severe symptoms total effective contrast, significant differences (P 0.