2型糖尿病患者视网膜病变相关危险因素分析.docVIP

2型糖尿病患者视网膜病变相关危险因素分析 　　[摘要] 目的 分析2型糖尿病患者视网膜病变的相关危险因素。 方法 以本院2012年8月~2014年2月收治的206例2型糖尿病患者为研究对象，其中观察组62例合并视网膜病变，未合并视网膜病变的144例作为对照组，比较分析两组的年龄、病程、体质指数、空腹血糖、糖化血红蛋白、尿微量白蛋白、尿素氮、血脂和血压等。 结果 单因素分析提示，年龄、病程、空腹血糖、糖化血红蛋白、尿微量白蛋白、尿素氮是该病的相关性因素；Logistic多因素分析提示，病程、糖化血红蛋白、尿微量白蛋白、尿素氮是该病的独立危险因素。 结论 病程、糖化血红蛋白、尿微量白蛋白、尿素氮是2型糖尿病视网膜病变的主要危险因素。 　　[关键词] 2型糖尿病；视网膜病变；危险因素 　　[中图分类号] R781.6+4[文献标识码] A[文章编号] 1674-4721（2014）06（c）-0034-02 　　 　　Relevant risk factors analysis of retinopathy in patients with type 2 diabetes mellitus 　　HUANG Yao-hui LIANG Zhen 　　Department of General medicine,the Second People′s Hospital ofShenzhen City,Shenzhen518035,China 　　[Abstract] Objective To analyze relevant risk factors of retinopathy in patients with type 2 diabetes mellitus. Methods 206 patients with type 2 diabetes mellitus treated in our hospital from August 2012 to February 2014 were selected as research objects, among them,there were 62 cases of the observation group with retinopathy,144 cases having no retinopathy were selected as the control group,and age,course of the disease,body masse,fastingglucose,glycosylatedhemoglobin, urine microalbumin,ureanitrogen,blood fat,blood pressure and so on of the two groups were comparatively analyzed. Results Mono-factor analysis showed that age,course of the disease,fastingglucose,glycosylatedhemoglobin, urine microalbumin,ureanitrogen were relevant factors of this disease,Logistic regression multi-factor analysis showed that course of the disease,glycosylated hemoglobin,urine microalbumin,urea nitrogen were independent risk factors. Conclusion Course of the disease,glycosylatedhemoglobin,urine microalbumin,urea nitrogen were main risk factors of type 2 diabetic retinopathy. 　　[Key words] Type 2 diabetes mellitus;Retinopathy;Risk factors 　　糖尿病视网膜病变（diabetic retinopathy，DRP）是糖尿病常见的并发症，是眼底特异性病变的一种，对视力功能影响极为严重，是致盲的主要病因之一，相关报道指出其在所有致盲病因中占1/5[1]。据统计，世界范围内的2型糖尿病人数约1.5亿，我国近年来2型糖尿病的发病率呈不断上升趋势，该并发症也随之增加，给患者的正常生活、工作造成诸多不便[2]。加强DRP相关危险因素的分析，对其临床预防和治疗均有重要临床意义，本研究详细分析2型