VISIA对强脉冲光联合注射除皱治疗面部皮肤老化定量评价.docVIP

VISIA对强脉冲光联合注射除皱治疗面部皮肤老化定量评价 　　[摘要]目的：观察VISIA图像分析系统对面部皮肤老化联合治疗前后的定量评价能力。方法：选取36名面部皮肤老化患者行强脉冲光治疗5次（每4周1次），合并A型肉毒毒素注射治疗1～2次。对治疗前后的皮肤相关特征进行检测，将测试结果进行对比分析，并计算差异性。结果：检测面部皮肤老化患者的不同皮肤特征在治疗前后的改善情况各不相同，治疗后面部斑点、毛细血管扩张、毛孔、皱纹较治疗前数值明显升高，两组对比具有显著性差异（P0.01）。结论：通过VISIA 图像分析系统对皮肤老化患者治疗前、后进行定量分析，可以作为疗效的一个定量衡量标准，在疗效评估上有一定意义。 　　[关键词]VISIA图像分析系统；强脉冲光；注射除皱；面部皮肤老化 　　[中图分类号]R454.2 [文献标志码]A [文章编号]1008-6455（2015）11-0060-03 　　Abstract： Objective To observe VISIA Complexion Analysis System Quantitative evaluation ability on facial skin aging before and after combined treatment. Methods 36 patients with facial skin aging were selected for intense pulsed light treatment for five times，Once every four weeks，and combined with botulinum toxin injections 1-2 times in the meaning time.Skin related characteristics were detected before and after treatment，and the results were contrastive analyzed and then the differences were calculated. Results The improvement of different skin characteristics detected by VISA in patients with facial skin aging was not identical，the differences were significant before and after treatment（P0.05）. Conclusion VISIA skin detector can be applied for quantitative analysis before and after treatment in the patients with skin aging.The data of spots， red blood，pores，and wrinkles after treatment were obviously higher than before treatment，the contrast of the two groups was significantly different （P0.01）. 　　Key words：VISIA complexion analysis system；intense pulsed light；injection of anti-wrinkle treatment；facial skin aging 　　面部皮肤的老化可分为自然老化和光老化，临床常表现为面部色素斑、皱纹、毛孔粗大、肤色晦暗等。Nouveau等[1]报道亚洲女性40岁以后皱纹会明显增多。随着社会经济的发展，人们对延缓皮肤衰老的需求越来越迫切。目前治疗皮肤老化的方法众多，但往往缺乏术前对患者不同皮肤特征的定量分析，同时缺乏对术后疗效的定量对比。本实验对36例皮肤老化患者通过VISIA图像分析系统在治疗前、后进行定量分析对比，现将结果报道如下。 　　1 资料和方法 　　1.1 临床资料 　　面部皮肤老化患者36例，均为女性，年龄35～50岁，平均年龄40.8岁。Fitzpatrick分型 III～IV型皮肤。临床表现：肤色晦暗28例、毛孔粗大25例、面部色素斑36例、不同程度的皱纹36例、毛细血管扩张16例，所有患者同时合并上述两种以上皮肤损害。排除标准：妊娠期及哺乳期妇女；治疗区域有开放性创面或感染性皮肤病灶患者；瘢痕体质者；心、肝、肾功能异常者；重症肌无力者；过敏性皮肤或自身免疫性皮肤病活动期患者。 　　1.2 仪器设备