不同剂量布托啡诺在宫腔镜术麻醉中应用效果.docVIP

不同剂量布托啡诺在宫腔镜术麻醉中的应用效果 　　[摘要] 目的 观察不同剂量布托啡诺在宫腔镜手术中的麻醉效果。 方法 选择2012年3～5月在我院拟行宫腔镜手术的子宫内膜息肉患者200例，ASAⅠ～Ⅱ级。将其随机分为A、B、C，D四组，每组50例。A、B、C组：丙泊酚分别复合5、10、15 μg/kg的布托啡诺，静脉注射，做宫腔镜手术的麻醉。D组单独用丙泊酚静脉麻醉。观察四组患者术中MAP、HR、SpO2及术中呼吸抑制的发生率、丙泊酚的总用量、意识恢复时间、定向力回复时间、术后宫缩痛的发生率。 结果 A、B、C、D四组的MAP、HR、SpO2略有下降，差异无统计学意义（P0.05）。A组术后意识恢复时间和定向力恢复时间明显短于B、C、D三组，差异有统计学意义（P0.05）。D组术后宫缩痛的发生率明显高于A、B、C三组，差异有统计学意义（P0.01）。 结论 丙泊酚复合适当剂量（5 μg/kg）的布托啡诺用于宫腔镜手术的麻醉，可减少丙泊酚的用量，有效降低患者术后宫缩痛的发生率，且不影响苏醒质量，是宫腔镜手术理想的麻醉方法。 　　[关键词] 不同剂量；布托啡诺；丙泊酚；宫腔镜手术 　　[中图分类号] R614.2+4 [文献标识码] A [文章编号] 1674-4721（2016）05（b）-0087-03 　　[Abstract] Objective To observe the anesthetic effect of butorphanol in different doses in hysteroscopic surgery. Methods Two hundred patients with endometrial polyp in ASAⅠ-Ⅱ in our hospital from March to May 2012 were selected.They were evenly divided into group A，group B，group C，and group D in random.In group A，group B，and group C，propofol combined with butorphanol in 5，10，15 μg/kg for intravenous injection were as anesthesia in hysteroscopic surgery.In group D，only propofol was used for intravenous anesthesia.Mean arterial pressure （MAP），heart rate （HR），oxyhemoglobin saturation（SpO2），incidence of respiratory depression during surgery，total dosage of propofol，consciousness recovery time，orientation recovery time，and incidence of pain of uterus systole after surgery among four gorups were observed. Results Among group A，group B，group C，and group D，MAP，HR，and SpO2 was slightly decreased respectively but without statistical difference（P0.05）.The incidence of respiratory depression in group C was a bit more than that in group A，group B，and group D，which was not displayed a statistical difference（P0.05）.The consteroscopic recovery time and orientation recovery time in group A was much shorter respectively in comparison with that in group B，group C，and group D with a statistical difference（P 　　[Key words] Different dosages；Butorphanol；Propofol；Hysteroscopic surgery 　　我院从2005年开始做宫腔镜手术，一年大约做1500例。我院采用丙泊酚单纯静脉麻醉，但