变应原免疫治疗进展2016课件.pptxVIP

变应原免疫治疗研究进展The progress of Allergen Immunotherapy research重庆新桥医院程晓明Mar 27th 2016 重庆变应性疾病-如影相随Gupta R, et al. BMJ. 2003 Nov 15x;327(7424):1142-3Ninan TK, et al. BMJ. 1992 Apr 4;304(6831):873-5历史变迁Von PirquetLarché M, et al. Nat Rev Immunol. 2006;6(10):761-71是Specific Immunotherapy (SIT) 还是Allergen Immunotherapy (AIT)?Calderón MA, et al. Allergy. 2013;68(7):825-8AIT的机制是什么？Induction of Treg and Breg cells suppression of Th2-Th1 cellsDecreased numbers of tissue mast cells and eosinophils and release of their mediators in nasal mucosal biopsies of allergic rhinitis patientsDecreased skin late-phase