人免疫球蛋白佐治小儿麻疹合并肺炎疗效观察.docVIP

人免疫球蛋白佐治小儿麻疹合并肺炎的疗效观察 　　【摘要】目的观察静注人免疫球蛋白（PH4）联合喜炎平对麻疹合并肺炎的治疗效果。 　　方法将收治的156例麻疹合并肺炎患儿按照入院时编号分组，双号为观察组，采用PH4联合喜炎平治疗，单号为对照组，单用喜炎平治疗，对比两组的疗效及各项观察指标恢复正常所需的时间。 　　结果观察组总有效率明显高于对照组（P0.001），各项生化指标恢复正常的时间及临床症状消失或明显减轻的时间少于对照组（P0.001）。 　　结论对麻疹合并肺炎患儿联合PH4和喜炎平治疗具有较好的疗效，值得在临床上推广使用。 　　【关键词】静注人免疫球蛋白；喜炎平注射液；麻疹；肺炎 　　中图分类号：R511.1；R725.6文献标识码：ADOI：10.3969/j.issn2016.02.018 　　【Abstract】ObjectiveTo observe the effect of human immune （PH4） combined with Xiyanping injection for children with measles complicated with pneumonia. 　　Methods156 cases of measles complicated with pneumonia were divided into observation group（even numbers） and control group（odd numbers） according to their hospital admission numbers. The observation group were given PH4 combined with Xiyanping injection， while the control group were given Xiyanping only. Then， curative effects and the time needed for each observation index returning to normal level were compared between groups. 　　Results Total effective rate in the observation group was significantly higher than that in the control group（P0001）. Time needed for each observation index returning to normal level， time for eliminating the clinical symptoms or time for reducing the clinical symptoms in the observation group was significantly less than those in the control group（P0001）. 　　ConclusionPH4 combined with Xiyanping injection has good efficacy for children with measles complicated with pneumonia， which is worthy of promotion and use in clinical practice. 　　【Key words】PH4 by intravenous injection； Xiyanping injection； measles； pneumonia 　　麻疹由麻疹病毒引起，是小儿常见的急性呼吸道传染性疾病，好发于免疫力较弱的婴幼儿[1]，如得不到及时而有效的治疗，极易产生多种并发症，肺炎是其中最常见的并发症之一，患儿常表现为发热、咳嗽、肺部??音、皮疹等多种症状[2]，不仅对患儿的生存质量造成严重的影响，而且有可能导致患儿死亡。近年来，中药制剂在麻疹的治疗上也取得了较好的成效，有研究显示静注人免疫球蛋白（PH4）对麻疹合并肺炎具有较好的疗效[3]，2013年2～6月我县暴发麻疹疫情，现将收治的156例麻疹合并肺炎的住院患儿作为观察对象，探讨同时使用PH4和喜炎平治疗的效果，现报道如下。 　　1资料与方法 　　1.1一般资料 　　收集2013年2～6月到我院儿科住院治疗的156例麻疹合并肺炎患儿，将所有患儿按照其入院时单双号进行分组，单号为对照组，共78例，其中男40例，女38例，年龄1～5岁，平均（2.57±0.51）岁；病程3～6 d，平均（4.0