高血压合并危险因素2课程.pptVIP

* 另一项发表于高血压杂志的荟萃分析共纳入26个ACEi/ARB同安慰剂/其他类药物比较的大规模研究，以评估ACEi和ARB的血压依赖或独立于降压之外的，对主要心血管事件的影响。结果显示，ACEI在降压以外显著降低冠心病风险达9%，而ARB增加了冠心病风险达8%。因此，ACEi降压外的心血管保护要显著优于ARB J Hypertens. 2007 May;25(5):951-8. Blood pressure-dependent and independent effects of agents that inhibit the renin-angiotensin system. Blood Pressure Lowering Treatment Trialists Collaboration, Turnbull F, Neal B, Pfeffer M, Kostis J, Algert C, Woodward M, Chalmers J, Zanchetti A, MacMahon S. Abstract OBJECTIVES: To evaluate the blood pressure-dependent and independent effects of angiotensin-converting enzyme inhibitors (ACEI) and an