前列地尔治疗慢性肾功能不全疗效观察.docVIP

前列地尔治疗慢性肾功能不全疗效观察 　　[摘要] 目的 探究慢性肾功能不全患者应用前列地尔治疗的临床效果。方法 随机选取该院2008年9月―2014年10月住院部60例慢性肾功能不全患者作为该次医学研究对象，所有患者均采取随机数字表法分为实验组与对照组，两组患者采取不同的治疗方案进行临床治疗，对照组患者予以常规保肾药物治疗，实验组患者在对照组治疗基础上加用前列地尔治疗，观察对比两组患者治疗临床效果、不良反应及血肌酐、血尿素氮、血尿酸、24 h尿量等各项指标变化情况。 结果 两组患者经临床治疗后疗效比较，实验组总有效率为90.00%，对照组为76.67%，实验组显著高于对照组，差异有统计学意义（P0.05）。结论 慢性肾功能不全患者在常规治疗的基础上联合前列地尔治疗具有显著的临床效果，可提升治疗总有效率，明显改善患者血肌酐、血尿酸及24 h尿量等各项指标，且不良反应少，安全性高，具有较高的临床推广与应用价值。 　　[关键词] 常规治疗；前列地尔；慢性肾功能不全；不良反应 　　[中图分类号] R692.5 [文献标识码] A [文章编号] 1674-0742（2015）09（a）-0147-02 　　To Observe the Curative Effect of Alprostadil in The Treatment of Chronic renal Insufficiency 　　ZHU Jue 　　Department of internal medicine， Peoples Hospital of Liyang City，Liyang， Jiangsu Province，213300 China 　　[Abstract] Objective To explore the application among patients with chronic renal insufficiency， the clinical effect of treatment. Methods Selected from September 2008 to October 2014 the inpatient 60 cases of patients with chronic renal insufficiency as the medical research object， all the patients were taken random number table method was divided into experimental group and control group， two groups of patients take different treatment for clinical treatment， control group patients give regular kidney drug treatment， treatment group patients in the control group on the basis of the total lead to treatment， observation compared two groups of patients clinical effect， adverse reaction and serum creatinine， blood urea nitrogen， blood uric acid， urine volume changes the indicators such as 24 hours a day. Results Two groups of patients after treatment with clinical curative effect comparison of the experimental group， the total effective rate was 90.00% in the control group was 76.67%， the experimental group was significantly higher than that of control group， P 0.05）.Conclusion Patients with chronic renal insufficiency in the united front on the basis of conventional treatment， treatment has significant clinical effect， can promote total effective treatmen