前列地尔联合疏血通注射液治疗急性脑梗死疗效观察.docVIP

前列地尔联合疏血通注射液治疗急性脑梗死疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.19.56 　　摘 要 目的：观察前列地尔联合疏血通注射液治疗急性脑梗死的临床疗效。方法：将80例急性脑梗死患者随机分为两组，前列地尔联合疏血通注射液组（联合组）及对照组，各40例。对两组治疗后巴塞尔指数（Barthel index，BI）、改良的Rankin scale（mRS）和减少的美国国立卫生研究所脑卒中评分（The National Institutes of Health Stroke Scale，NIHSS）百分数进行评估，分析两组临床疗效的差别。结果：治疗后联合组的BI及减少的NIHSS百分数均明显高于对照组（P0.01，P0.05），而mRS明显低于对照组（P0.01）。结论：联合应用前列地尔和疏血通注射液治疗急性脑梗死可达到协同互补的作用，能够有效改善患者的神经功能缺损程度。 　　关键词 急性脑梗死 前列地尔注射液 疏血通注射液 　　Curative effect observation of alprostadil combined with Shu Xue Tong injection in the treatment of acute cerebral infarction 　　Liu Zuyou，Qi Feng，Yu Ke，Wei Zhaoxia，Xu Xuan 　　Internal Medicine-Neurology，Liwan Hospital Affiliated to Guangzhou Medical College（Guangzhou City，Guangdong） 510170 　　Abstract Objective：To explore the curative effect of alprostadil combined with Shu Xue Tong injection in the treatment of acute cerebral infarction.Methods：80 cases with acute cerebral infarction were randomly divided into the alprostadil combined with Shu Xue Tong injection group（combined group） and the control group with 40 cases in each.We evaluated the barthel index，improved rankin scale and reduced the national institutes of health stroke scale percentage after treatment of the two groups，and analyzed the difference of clinical curative effect of two groups.Results：After treatment，the BI and reduced NIHSS percentage of combined group were significantly higher than those in control group（P0.01，P0.05），while mRS was significantly lower than that of the control group（P0.01）.Conclusion：The application of alprostadil combined with Shu Xue Tong injection in the treatment of acute cerebral infarction can achieve the coordination effect，and it can effectively improve the neurological function defect degree. 　　Key words Acute cerebral infarction；Alprostadil Injection；Shu Xue Tong injection 　　脑血管疾病（cerebrovascular disease，CVD）是神经系统的常见病及多发病，是目前人类疾病的三大死亡原因之一，存活者中50%～70%遗留瘫痪、失语等严重残疾，给社会和家庭带来沉重的负担。其中缺血性卒中的发病率很高，占全部脑血管病的50%以上。本研究应用前列地尔联合疏血通注射液治疗急性