参芎葡萄糖注射液治疗急性脑梗死效果及对神经功能与血液流变学影响.docVIP

参芎葡萄糖注射液治疗急性脑梗死效果及对神经功能与血液流变学影响 　　[摘要]目的 探?参芎葡萄糖注射液治疗急性脑梗死的效果及对神经功能与血液流变学的影响。方法 选取2014年12月～2016年4月我院收治的114例急性脑梗死患者，随机均分为研究组和对照组。对照组在常规治疗的基础上使用曲克芦丁脑蛋白水解物治疗，研究组在常规治疗的基础上使用曲克芦丁脑蛋白水解物联合参芎葡萄糖注射液治疗。比较两组患者治疗总有效率、治疗前后神经功能缺损评分、血液流变学参数及生活质量评分的差异。结果 研究组治疗总有效率为80.7%，高于对照组的61.4%，差异有统计学意义（P0.05）；治疗后15、30、60 d，研究组神经功能缺损评分均比对照组低（P0.05）；治疗后，研究组全血高切黏度、全血低切黏度、血细胞比容、血小板聚集均比对照组低，差异有统计学意义（P0.05）。治疗后，研究组生活质量评分高于对照组，差异有统计学意义（P0.05）。结论 参芎葡萄糖注射液治疗急性脑梗死效果肯定，能有效恢复患者神经功能，改善血液流变学状态，提高患者的生活质量，值得临床推广应用。 　　[关键词]参芎葡萄糖注射液；急性脑梗死；血液流变学；脑蛋白水解物 　　[中图分类号] R743.33 [文献标识码] A [文章编号] 1674-4721（2016）12（a）-0044-03 　　Effects of Shenxiong Glucose Injection in the treatment of acute cerebral infarction and its effect on nerve function and hemorrheology 　　LIAO Hua-yin HU Qiong-li BAO Ze-yan ZHONG Shui-sheng 　　The Second Department of Neurology，Guangdong 999 Brain Hospital in Guangdong Province，Guangzhou 510510，China 　　[Abstract]Objective To investigate effects of Shenxiong Glucose Injection in the treatment of acute cerebral infarction and its effect on nerve function and hemorrheology.Methods 114 cases of acute cerebral infarction patients in our hospital from December 2014 to April 2016 were selected and randomly divided into research group and control group，57 cases in each group.Patients in the control group were treated with Troxerutin brain protein hydrolyzate based on conventional therapy，patients in the research group were treated with Shenxiong Glucose Injection combined with Troxerutin brain protein hydrolyzate.The total effective rate，neurological deficit scores，hemorheolog parameter and SF-36 score for evaluating quality of life before and after treatment of two groups were compared.Results The total effective rate in the research group was 80.7%，higher than 61.4% in the control group，and the difference was statistically significant （P0.05）.After treatment of 15，30 and 60 d，the neurological deficit scores in the research group was lower than that in the control group （P 　　[Key words]Shenxiong G