参芪扶正注射液联合姑息性化疗对晚期结直肠癌疗效临床观察.docVIP

参芪扶正注射液联合姑息性化疗对晚期结直肠癌疗效临床观察 　　摘 要：目的 ?^察晚期结直肠癌姑息性化疗中联合应用参芪扶正注射液的疗效。方法 将118例晚期结直肠癌患者随机分为治疗组（参芪扶正注射液联合姑息性化疗）61例和对照组（单纯姑息性化疗组）57例，对比观察两组患者3周期姑息性化疗后的总体有效率、化疗不良反应和生活质量改善情况。结果 治疗组总有效率77.05%，对照组56.14%，治疗组总有效率明显优于对照组，两组间差异显著（P0.05）；治疗组患者胃肠道反应、骨髓抑制等不良反应发生率均显著低于对照组（P0.05）；患者生存质量改善情况治疗组（68.85%）优于对照组（49.12%），两组差异有统计学意义（P0.05）。结论 晚期结直肠癌患者姑息性化疗联合应用参芪扶正注射液，能够取得较好疗效，同时减轻化疗不良反应、改善生活质量。 　　关键词：参芪扶正注射液；姑息性化疗；晚期结直肠癌；生活质量 　　中图分类号：R735.3+7 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.01.054 　　文章编号：1006-1959（2018）01-0140-03 　　Clinical Observation on Effect of Shenqi Fuzheng Injection Combined with Palliative Chemotherapy in Patients with Advanced Colorectal Cancer 　　GONG Quan，WANG Cun-de，LI Jiang-long，LI Shi-juan，SHI Wei 　　（Palliative Medicine，The Third Affiliated Hospital of Kunming Medical University，Yunnan Cancer Hospital/Yunnan Palliative Medicine Research Center，Kunming 650118，Yunnan，China） 　　Abstract：Objective To observe the curative effect of advanced colorectal cancer palliative chemotherapy combined application of Shenqi Fuzheng injection.Methods 118 patients with advanced colorectal cancer were randomly divided into treatment group（Shenqi Fuzheng injection combined with palliative chemotherapy）in 61 cases and control group（simple palliative chemotherapy group）57 cases，comparison of two groups of patients with total 3 cycles of palliative chemotherapy after the efficacy and adverse reaction of chemotherapy and improve the quality of life.Results The total effective rate was 77.05% in treatment group and 56.14% in the control group，the total effective rate of treatment group was significantly better than the control group，the difference between the two groups was significant（P0.05）；the treatment group patients with gastrointestinal reaction the adverse reaction， bone marrow suppression rate were significantly lower than control group（P0.05）；improve the quality of life of patients with the treatment group （68.85%）better than the control group（49.12%），there was significant diff