复方阿嗪米特联合胆宁片治疗胆源性消化不良临床研究.docVIP

复方阿嗪米特联合胆宁片治疗胆源性消化不良临床研究 　　【摘要】 目的 观察复方阿嗪米特联合胆宁片治疗胆源性消化不良的临床效果。方法 139例胆源性消化不良的患者随机分为治疗组（71例）和对照组（68例）， 治疗组给予复方阿嗪米特联合胆宁片治疗， 对照组仅给予胆宁片治疗。分别于治疗1、2、4周末记录临床症状观察结果， 对比两组的疗效及不良反应。结果 治疗组症状明显改善， 在1、2、4周时总有效率分别达40.8%、88.7%、100.0%， 均明显高于对照组（19.1%、45.6%、51.5%）， 两组疗效比较差异有统计学意义（Plt;0.05）。两组不良反应及停药后复发率比较差异无统计学意义（Pgt;0.05）。结论 复方阿嗪米特联合胆宁片治疗胆源性消化不良疗效好， 起效快， 安全性好。 　　【关键词】 胆源性消化不良;胆宁片;复方阿嗪米特 　　DOI：10.14163/j.cnki.11-5547/r.2015.03.004 　　Clinical research of compound azintamide combined with Danning tablets in the treatment of biliary dyspepsia JIN Shu-li， LI Li-ping， LI Zi-xian. Henan Puyang City Anyang District Hospital， Puyang 455000， China 　　【Abstract】 Objective To observe the clinical effect of compound azintamide combined with Danning tablets in the treatment of biliary dyspepsia. Methods A total of 139 biliary dyspepsia patients were randomly divided into treatment group （n=71） and control group （n=68）. The treatment group received compound azintamide combined with Danning tablets for treatment， while the control group received Danning tablets alone. Observation results of clinical symptoms in 1 week， 2 and 4 weeks of treatment were recorded， and the curative effects and adverse reactions were compared between the two groups. Results The symptoms in the treatment group were significantly improved. The total effective rates in 1 week， 2 weeks， and 4 weeks were respectively 40.8%， 88.7%， and 100.0%， which were higher than the control group （19.1%， 45.6%， and 51.5%）. The difference of curative effects between the two groups had statistical significance （Plt;0.05）. There was no statistically significant difference of adverse reactions and recurrence rates after drug withdrawal between the two groups （Pgt;0.05）. Conclusion The combination of compound azintamide and Danning tablets has good effect， quick efficiency， and high safety in the treatment of biliary dyspepsia. 　　【Key words】 Biliary dyspepsia; Danning tablets; Compound azintamide 　　消化不良从病因上分为功能性消化不良（FD）和器质性消化不良（OD），