多囊卵巢综合征胰岛素抵抗患者饮食控制及药物干预对近远期并发症影响研究.docVIP

多囊卵巢综合征胰岛素抵抗患者饮食控制及药物干预对近远期并发症影响研究 　　【摘要】目的：研究关于多囊卵巢综合征胰岛素抵抗患者饮食控制和药物干预对近、远期并发症造成的相关影响。方法：选取2012年8月至2014年8月期间在我院收治的150例多囊卵巢综合征胰岛素抵抗患者，并随机将150例患者分成研究组与参照组两组。研究组患者80例，参照组患者70例。对研究组与参照组的患者进行干预以后，观察患者体重指标、体温情况、月经的周期以及内分泌状态和卵泡发育情况。妊娠以后，统计两组患者的合并糖尿病情况，以及巨大儿的发病率，并对参照组与研究组患者的代谢性疾病转归进行仔细观察。结果：在经过饮食控制与药物干预以后，研究组的患者在妊娠期糖尿病以及巨大儿的发病率上明显低于参照组，并观察两年期间患者的糖尿病以及高血压的发病情况研究组具有显著的较参照组低的结果。结论：多囊卵巢综合征胰岛素抵抗患者饮食控制和药物干预对近、远期并发症具有重要的影响作用。通过帮助多囊卵巢综合征胰岛素抵抗患者建立起科学健康的饮食习惯，适当的运动，并服用胰岛素增敏剂，能够有效的降低并发症的发生率，推动女性患者尽快恢复健康。 　　【关键词】多囊卵巢综合征；胰岛素抵抗；饮食及药物干预；并发症 　　Effect of diet control and drug intervention on short and long term complication in patients with polycystic ovary syndrome and insulin resistanceWANG Shuhua1， HUANG Jianhui2， GUAN Hongli1. 1.Department of Obstetrics and Gynecology， Neijiang City Traditional Chinese Medicine Hospital， Neijiang 641000， Sichuan， China； 2.Department of Severe Medicine， Luzhou Hospital of Traditional Chinese Medicine， Luzhou 646000， Sichuan， China 　　【Abstract】Objectives： To study the effect of diet control and drug intervention on short and long term complications in patients with polycystic ovary syndrome and insulin resistance. Methods： 150 patients with polycystic ovarian comprehensive syndrome with insulin resistance in our hospital from August 2012 to August 2014 were randomly divided into two groups， study group and control group. There were 80 patients in study group and 70 patients in control group. After intervention， body weight index， body temperature， menstrual cycle and endocrine and follicular development of study group and control group were observed. After pregnancy， the incidences of macrosomia and diabetes occurrence were analyzed. Metabolic disease outcome of two groups was observed. Results： After diet control and drug intervention， the incidences of macrosomia and diabetes occurrence in study group were lower than these in control group. Diabetes and hypertension incidences of study group were significant lower than these in control group during