孟鲁司特钠辅助治疗儿童支原体肺炎可行性分析.docVIP

孟鲁司特钠辅助治疗儿童支原体肺炎可行性分析 　　[摘要]目的 通?^观察患儿的临床表现，探讨分析孟鲁司特钠辅助治疗儿童支原体肺炎的可行性。方法 选取2014年8月～2016年7月在我院接受治疗的62例支原体肺炎患儿作为研究对象，按照随机数字表法将其分为对照组（n=30）和观察组（n=32）。对照组患儿采用阿奇霉素静滴和布地奈德雾化吸入的方法进行治疗，观察组患儿在对照组治疗方法的基础上增加孟鲁司特钠口服的方法进行治疗。观察记录两组患儿的相关临床指标数据，包括治疗总有效率、相关症状缓解时间、住院时间、并发症发生率、血气分析情况等。结果 观察组患儿的治疗总有效率显著高于对照组，差异有统计学意义（P0.05）。观察组患儿的咳嗽、体温下降、??音消失和住院时间均短于对照组，且肺外并发症的发生率也低于对照组，差异均有统计学意义（P0.05）。观察组患儿治疗后的一秒用力呼气容积（FEV1）、FEV1/用力肺活量（FVC）、最大呼气流量（PEF）均高于对照组，差异有统计学意义（P0.05）。观察组患儿治疗后的氧分压（PO2）含量高于对照组，二氧化碳分压（PCO2）含量低于对照组，差异有统计学意义（P0.05）。结论 在治疗儿童支原体肺炎时，孟鲁司特钠具有显著效果，可有效推进患儿的治疗进程，改善相关临床症状，促使患儿的肺功能得到恢复，且具有较高的安全性，因而可在临床上进行推广应用。 　　[关键词]孟鲁司特钠；小儿；支原体肺炎；辅助治疗 　　[中图分类号] R722.5 [文献标识码] A [文章编号] 1674-4721（2018）4（a）-0147-04 　　Feasibility analysis of Montelukast Sodium as an adjuvant treatment for Mycoplasma pneumonia in children 　　TAO Meng-jie 　　Department of Pediatrics，the Second People′s Hospital of Longgang District，Guangdong Province，Shenzhen 518112，China 　　[Abstract]Objective To investigate the feasibility of Montelukast Sodium as an adjuvant treatment in children with Mycoplasma pneumonia by observing their clinical manifestations.Methods Sixty-two children with Mycoplasma pneumonia who were treated in our hospital from August 2014 to July 2016 were selected as subjects.They were divided into the control group （n=30） and observation group （n=32） according to the random number table method.In the control group，pediatric patients were treated with intravenous infusion of Azithromycin and aerosol inhalation of Budesonide，while in the observation group，on the basis of the control group，Montelukast Sodium as oral administration was added.The relative clinical data including total therapeutic effectiveness rate，remission time of relevant symptoms，hospital stay，incidence of complications，and blood gas analysis were observed and recorded in the two groups.Results The therapeutic effectiveness rate in the observation group was significantly higher than that of the control group，and the difference was statisticall