WinMI软件优化设计与实现-生物医学工程专业论文.docxVIP

摘要 摘要 摘要 光学分子成像技术作为一种新兴的医学成像技术，由于其具有灵敏度高、安全 性好、操作简单的优势，已广泛应用于生物医学成像领域。但由于光在生物组织 中传播时具有较高的散射，这极大的限制了光学分子成像在深层组织中的应用。 开发用于小动物的在体光学成像系统，实现小动物的在体光学成像具有重要意义。 小动物在体光学分子成像系统可以实现生物自发光成像和激发荧光成像两种 成像模态的图像采集及图像处理功能。该系统由暗箱、科学级CCD相机以及软件 平台WinMI三部分组成。WinMI软件负责系统控制、数据采集及分析，是整个系统 的灵魂。本文围绕WinMI软件的优化设计与实现，首先介绍了WinMI软件的功能需 求，并对在开发维护中存在的问题进行了说明；之后具体介绍了软件的界面优化、 功能优化及增强等内容；最后通过设计软件测试和功能对比实验，验证了优化后 的软件性能。 关键词：光学成像 图像处理 优化设计 Ab Abstract Abstract As a new medical imaging technology, optical molecular imaging has been extensively applied in the biomedical research with the advantages of high sensitivity, low cost and simple operation. However, because of the high scattering of the biological tissues, the optical molecular imaging has been greatly limited in the imaging of the deep tissue. Therefore, it is essential and important to develop a small animal in vivo optical imaging system and realize the optical imaging. The small animal in vivo optical molecular imaging system consists of a control chamber, a scientific grade CCD camera and a software platform WinMI, which can accomplish the data acquisition and processing of the bioluminescence imaging and fluorescence imaging. Especially, the WinMI software takes charge of the system control, image acquisition and data analysis. This paper focuses on the design and implementation of the WinMI software optimization. At the beginning, we introduce the functional requirements of the software and the questions during the maintenance; then we have a detailed discussion on the interface optimization, the functional optimization and enhancement; in the end, through software testing and a contrast experiment, we verify the performance of the software. Keyword: Molecular imaging Imaging processing Optimal design 目录 目录 HYPERLINK \l _bookmark0 第一章 绪论 1 HYPERLINK \l _bookmark1 1.1 研究背景 1 HYPERLINK \l _bookmark2 1.2 在体光学分子影像技术概述 2 HYPERLINK \l _bookmark3 1.2.1 生物自发光成像概述 2 HYPERLINK \l _bookmark5 1.2.2 激发荧光成像概述 4 HYPERLINK \l _bookmark6 1.3