护理干预对非小细胞肺癌晚期化学治疗患者生存质量影响.docVIP

护理干预对非小细胞肺癌晚期化学治疗患者生存质量影响 　　[摘要] 目的 探?护理干预对非小细胞肺癌晚期化学治疗患者生存质量的影响。 方法 从我院2015年5月～2016年5月期间收治的非小细胞肺癌晚期患者中随机抽取82例作为研究对象，按照随机数字表法分为两组：对照组41例患者给予常规化学治疗和护理，观察组41例患者在对照组的基础上加以综合性护理干预，采用肺癌患者生存质量测定量表（FACT-L）第四版统计两组患者护理前后生存质量，统计不良反应发生情况。 结果 两组护理前的生活质量指标比较无显著差异（P0.05）；观察组护理后的情感状况评分和附加的关注情况评分较护理前显著提高（P0.05）。观察组消化道反应、骨髓抑制、肾毒性、神经毒性及皮肤黏膜损伤发生率分别为29.27%、19.51%、12.20%、14.63%、19.51%，均较对照组显著降低（P0.05）。 结论 在化学治疗同时给予非小细胞肺癌晚期患者综合护理干预措施，可显著提高患者生存质量，降低不良反应发生率。 　　[关键词] 非小细胞肺癌；护理干预；生存质量；化学治疗 　　[中图分类号] R473.73 [文献标识码] A [文章编号] 2095-0616（2017）08-134-04 　　[Abstract] Objective To explore the effect of nursing intervention on quality of life of patients with advanced non-small cell lung cancer treated with chemotherapy. Methods 82 cases of patients with advanced non-small cell lung cancer cured in our hospital from May 2015 to May 2016 were randomly selected as the study objects. According to random digital table method， they were divided into control group and observation group with 41 cases in each. Patients in control group were treated with routine chemotherapy and nursing care， and patients in observation group were treated with comprehensive nursing intervention on the basis of control group. Lung cancer patients quality of life scale （FACT-L） Fourth Edition was used to quality of life of two groups of patients before and after treatment， statistical adverse reactions. Results There was no significant difference between the two groups before nursing quality of life （P0.05）. The scores of emotional status and additional attention in the observation group were significantly higher than those before nursing （P0.05）. The incidence of gastrointestinal reaction， bone marrow suppression， nephrotoxicity， neurotoxicity and skin mucosal injury in the observation group were 29.27%， 19.51%， 12.20%， 14.63%， and 19.51%， respectively， which were significantly lower than those in the control group （P 　　[Key words] Non small cell lung cancer； Nursing intervention； Quality of life； Chemotherapy 　　化学治疗是中