改良岛状皮瓣在手部组织缺损与手指修复中临床应用.docVIP

改良岛状皮瓣在手部组织缺损与手指修复中临床应用 　　[摘要]目的 探?改良岛状皮瓣移植术在手部组织缺损与手指修复中的临床应用情况及临床疗效。 方法 选取前来我院急诊治疗的64例手部组织缺损及手指修复患者作研究对象，按随机数字表法分组，分为对照组和试验组，每组各32例，两组患者均予手术治疗，对患者进行彻底清创手术，对照组的修复采用普通岛状皮瓣移植术进行治疗，试验组予以改良岛状皮瓣移植术进行手部外伤创面修复。两组患者的临床有效率、炎性因子变化（IL-6、IL-10、TNF-α）、不良反应发生率等情况进行统计比较。 结果 试验组有效率90.63%明显高于对照组有效率68.75%，差异有统计学意义（P0.05）。治疗后，患者血清IL-6、IL-10、TNF-α水平降低，治疗组血清IL-6、IL-10、TNF-α水平低于对照组（P0.05）。试验组不良反应发生率（18.75%）明显低于对照组（43.75%），差异有统计学意义（P0.05）。 结论 发，降低炎性反应、减少患者并发症的发生概率，适宜临床推广应用。 　　[关键词] 岛状皮瓣术；改良岛状皮瓣术；手部组织缺损；手指修复 　　[中图分类号] R64 [文献标识码] B [文章编号] 2095-0616（2017）16-14-04 　　Clinical application of modified island flap in hand tissue defect and finger repair 　　YANG Haoran YANG Yanbin 　　Department of Trauma Surgery， Guangdong No.2 Provincial Peoples Hospital Zhuhai Branch （Zhuhai High-Tech Zone Peoples Hospital）， Zhuhai 519000， China 　　[Abstract] Objective To explore the clinical application and clinical effect of modified island flap in hand tissue defect and finger repair. Methods 64 cases of hand tissue defect and finger repair cured in emergency treatment of our hospital were selected as the study object. According to the random number table method， they were divided into control and experimental groups， 32 cases in each group. All the patients in the two groups were treated by surgery. The patient underwent a thorough debridement. The patients in the control group were treated with conventional island flap transplantation， and the patients in experimental group was treated with modified island flap grafting for hand wound repair. The clinical efficiency， inflammatory factors （IL-6， IL-10， TNF-α）， and the incidence of adverse reactions of the two groups were statistically analyzed. Results The effective rate of the experimental group was 90.63%， which was obviously higher than that of the control group， the effective rate was 68.75%， the difference was statistically significant （P 　　[Key words] Island flap； Modified island flap； Hand tissue defect； Finger repair 　　作为人类日常生活中运用最为广泛的身体器官，手