最小ADC值对侧脑室中枢神经细胞瘤诊断和鉴别诊断价值.docVIP

最小ADC值对侧脑室中枢神经细胞瘤诊断和鉴别诊断价值 　　[摘要] 目的 通过最小ADC值分析，以提高对侧脑室中枢神经细胞瘤（CNC）诊断及鉴别诊断的准确性。 方法 回顾性分析江苏省人民医院2010年9月―2016年9月间经手术病理证实的41例侧脑室肿瘤的常规MRI、DWI表现，分成CNC组、室管膜瘤组，星形细胞瘤组，并对其最小ADC值进行统计分析。 结果 18例CNC DWI表现为高信号12例，稍高信号6例，平均最小ADC值为（0.65±0.13）×10-3 mm2/s；23例非CNC DWI为等或稍信号16例，低信号7例，其中12例室管膜瘤平均最小ADC值为（1.07±0.15）×10-3 mm2/s，11例星形细胞瘤平均最小ADC值为（1.14±0.19）×10-3 mm2/s；CNC组平均最小ADC值与其他两组差异有统计学意义；根据ROC曲线，当肿瘤最小ADC值为0.85×10-3 mm2/s，诊断CNC敏感性为94%，特异性为100%，阳性预测值为94%，阴性预测值为96%。结论 最小ADC值对于侧脑室CNC的术前诊断及鉴别诊断有明确的应用价值。 　　[关键词] 弥散加权成像；表观弥散系数；侧脑室；中枢神经细胞瘤 　　[中图分类号] R445 [文献标识码] A [文章编号] 1674-0742（2017）08（c）-0042-03 　　Value of Minmum ADC Value in Diagnosis and Differential Diagnosis of Paracoele Axoneuron Tumors 　　LI Chang-cheng1， WANG Min2 　　1.Department of Radiology， Lianyungang Oriental Hospital， Lianyungang， Jiangsu Province， 222042 China；2.Department of Radiology，the First Affiliated Hospital of Nanjing Medical University， Nanjing， Jiangsu Province， 210029 China 　　[Abstract] Objective To analyze the minimum ADC value in order to improve the diagnosis and differential diagnosis accuracy of CNC. Methods The routien MRI and DWI manifestations of 41 cases of patients with tumors of lateral cerebral ventricle proved by the operation from September 2010 to September 2016 were reviewed and divided into the CNC group， ependymoma group and astroma group， and the minimum ADC value was statistically analayzed. Results Of 18 cases， there were 12 cases whose CNC DWI manifestations were high signal and 6 cases with slightly high signal， and the average minimum ADC value was（0.65±0.13）×10-3 mm2/s， of 23 cases， there were 16 cases whose non- CNC DWI equal or slightly low signal， and 7 cases with low signal， and the average minimun ADC value of 12 cases of patients with ependymoma was （1.07±0.15）×10-3 mm2/s， the average mean ADC value of 11 cases of astrocytoma patients was（1.14±0.19）×10-3 mm2/s， and the difference in the average minimum ADC value between the CNC group and the other groups was statistically sign