紫薇提取物面部去皱作用研究.docVIP

紫薇提取物面部去皱作用研究 　　[摘要]目的：探讨紫薇提取物去除面部皮肤皱纹的临床疗效。方法：招募20名面部有明显皱纹、肌肤松弛的健康受试者。两侧眼外眦和鼻唇沟按照随机原则分为产品侧和对照侧，分别使用产品或对照品。于使用前、使用后28天和56天对受试部位皮肤进行皮肤弹性测量，同时对受试者眼外眦部位的皱纹进行临床评分。结果：使用56天后，受试者眼外眦、鼻唇沟部位产品侧受试者皮肤弹性度较对照侧出现明显改善（P0.05）。使用28和56天，受试者产品侧鱼尾纹评分与对照侧评分相比明显降低（P0.05）。结论：紫薇提取物对面部皱纹具有一定的去皱作用，安全性好。 　　[关键词]紫薇提取物；皮肤皱纹；去皱 　　[中图分类号]R655 [文献标识码]A[文章编号]1008-6455（2014）10-0820-04 　　 　　Study on Lagerstroemia indica extract getting rid of facial wrinkles 　　ZHANG Yun-qing1,YIN Song-chao1,GUAN Lei2,ZHANG Sai2,LI Huan3,LAI Wei1 　　(1.Department of Dermatology,The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630,Guangdong,China;2.Skin Research Center of Guangzhou Landproof;3.Department of Dermatology,The First Affiliated Hospital of Sun Yet-sen University) 　　 　　Abstract:ObjectiveTo investigate the clinical efficacy of Lagerstroemia indica extract getting rid of wrinkles.MethodsThe 20 subjects were recruited.The subjects coated with Lagerstroemia indica extract.One side of face was applied with the cosmetic according to randomization, the other side with the placebo,twice a day morning and evening,for the period of 56 days.Before and after testing,the subjects were measured the skin elasticity.The doctor clinical score were conducted at the same time.ResultsAt day 56 after use,the skin elasticity of product side were significantly improved than that of the control side at eye canthus outside and nasolabial sulcus（P0.05）.At day 28 and 56 after use,the crows feet scores of product side were significantly decreased compared with that of the control side（P0.05）.ConclusionThe cosmetic including Lagerstroemia indica extract can effectively reduce facial wrinkles, improve skin appearance,and have a good safety. 　　Key words:Lagerstroemia indica extract;facial wrinkle;reducing wrinkle 　　 紫薇(Lagerstroemia indica)，为千屈菜科紫薇属双子叶植物，分布于中国、朝鲜、澳大利亚等地。传统医学上紫薇的根、叶、皮入药，有清热解毒、活血止血之效[1]。还具有抗氧化[2]、抗菌[3]、抗炎[4]、抗肿瘤[5]等药理学活性，具有多种药用价值。鉴于植物具有抗氧化、抗衰老的作用，研究者热衷于将天然植物提取物制成温和、安全的护肤品达到去除皮肤皱纹的目的。Natural R