限制性液体复苏方法在活动性出血性休克患者前期治疗效果分析.docVIP

限制性液体复苏方法在活动性出血性休克患者前期治疗效果分析 　　[摘要] 目的 探讨限制性液体复苏方法在创伤性出血性休克患者的前期治疗效果。 方法 选取2012年1月～2013年12月在我科就诊的创伤性出血性休克患者80例，随机分为观察组和对照组，各40例，观察组给予限制性液体复苏方法治疗，对照组给予常规液体复苏法治疗，比较两组患者前期治疗效果。 结果 观察组的输液量、血红蛋白浓度、平均动脉血压、凝血酶原时间均明显低于对照组，差异有统计学意义（P0.05）；观察组的复苏后血浆TNF-α、IL-2的含量变化明显低于对照组，差异均有统计学意义（P0.05）；两组患者的病死率、并发症发生率明显低于对照组，差异均有统计学意义（P0.05）。 结论 限制性液体复苏方法在创伤性出血性休克患者前期具有较好的临床效果，能保证重要器官的血流供应，提高患者的治愈率，改善预后。 　　[关键词] 限制性液体复苏；创伤性出血性休克 　　[中图分类号] R459.7 [文献标识码] B [文章编号] 1673-9701（2015）11-0098-04 　　[Abstract] Objective To evaluate the effection of limited fluid resuscitation in early treatment of traumatic hemorrhagic shock patients. Methods A total of 80 cases with traumatic hemorrhagic shock patients were randomly divided into observation group and control group by tossing a coin from January 2012 to December 2013， with each 40 cases， the observation group was given the limited fluid resuscitation therapy， the control group was given conventional fluid resuscitation therapy. The officacy of two groups was analyzed. Results The infusion volume， hemoglobin concentration， mean arterial blood pressure， and prothrombin time of the observation group were significantly lower than those in the control group， with statistically significant difference（P0.05）. The TNF-α， IL-2 of the observation group were significantly lower than those in the control grous after resuscitation， with statistically significant differences（P0.05）. The fatality rate and the complication rate of the observation group were significantly lower than those in the control group， with statistically significant differences（P0.05）. Conclusion Limited fluid resuscitation on traumatic hemorrhagic shock patients early has good clinical effect， can ensure the blood supply to the important organs， improve the cure rate， improve prognosis. 　　[Key words] Limited fluid resuscitation； Hemorrhagic traumatic shock 　　限制性液体复苏是指创伤性失血性休克者在进行手术彻底止血前控制液体输入量，使限制液体的输入量仅够维持机体的基本需要，在手术止血后再进行大量的液体复苏[1，2]。 创伤性出血性休克发生率近年呈上升趋势，常见的病因主要有车祸伤、高空坠落、打架斗殴等。创伤性出血休