特罗凯说明书2013年.pdfVIP

2007 10 04 2009 01 19 2009 03 10 2009 09 30 2009 11 11 2010 04 28 2011 06 29 2012 10 23 2012 11 27 2013 12 05 ® Erlotinib Hydrochloride Tablets Yansuan Eluotini Pian N-(3-)-6,7-(2-)-4- C H N O ·HCl 22 23 3 4 429.90 1 33 NSCLC ++NSCLC 4 BO18192[] EGFR 1100 2150 150mg/ 1 2 ILD - 2 33 50mg CYP3A4 TAO CYP3A4 AUC 2/3-4/5 CYP3A4 150mg450mg CYP3A4 St. John’s Wort Child-Pugh 7-9