医学文库网-肝功能不全-病理生理学第8版.pptVIP

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医学文库网-肝功能不全-病理生理学第8版.ppt

医学文库网-肝功能不全-病理生理学第8版.ppt

* * 肠蠕动减弱 肉食、上消化道出血 * * * 经转氨基过程 * * * 止痛、镇静、麻醉 * 神经类固醇类物质 四氢孕烯醇酮(tetrahydropregnenolone, THP)和四氢脱氧皮质酮(tetrahydrodeoxycorticosterone, THDOC) * the most essential factors damaging the CNS are ammonia, mercaptans, biogenic beta-hydroxyl amines, short-chain fatty acids, natural substances with benzodiazepine activity, GABA, proinflammatory cytokines, manganese, nitric oxide, and others. Increases in the concentrations of these substances in the CNS favors or causes the impairment of nerve impulses at the synapses level, the neuronal membrane, and energy metabolism impairment in the neural tissu

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