481例不同年龄组国产和进口流感疫苗接种效果分析.docVIP

481例不同年龄组国产和进口流感疫苗接种效果分析 　　【摘要】 目的：比对进口和国产两个不同厂家流感病毒裂解疫苗（简称流感疫苗）的免疫效果。方法：通过电话及问卷回访的方式统计2013年9月-2014年3月在珠海市中大五院接种流感疫苗481例接种者接种流感疫苗半年内出现的普通感冒发生情况和流感样疾病发生情况。将其结果分6～35个月组和≥3岁组，并通过SPSS 19.0软件进行统计学分析，并讨论两种疫苗免疫效果的差异是否有意义。结果：对于进口和国产两种疫苗在6～35个月组组接种后，普通感冒发生率分别46.9%和44.2%，差异无统计学意义（P0.05），流感样疾病发生率分别1.9%和2.6%，差异无统计学意义（P0.05）；≥3岁组普通冒发生率分别为22.2%和32.0%，差异无统计学意义（P0.05）。流行性感冒发生率分别1.8%和1.3%，差异无统计学意义（P0.05）。结论：接种葛兰素史克和兰州生物流感疫苗的接种者在半年内患普通感冒和流行性感冒的几率无显著差异。 　　【关键词】 流感病毒裂解疫苗； 免疫效果； 进口和国产 　　中图分类号 R186 文献标识码 A 文章编号 1674-6805（2015）26-0012-03 　　Analysis the Effect of Inoculation of 481 Cases of Patients in Different Ages People Caused by Domestic and Imported Influenza Vaccine/LIN Dao-jian，WANG Hua-fang，MAI Wei-hua.//Chinese and Foreign Medical Research，2015，13（26）：12-14 　　【Abstract】 Objective：To compare the immunological effects of domestic and imported split influenza virus vaccine （Influenza Vaccine for short）.Method：Using telephone and questionnaire to communicate with the 481 people who took the Influenza Vaccine in The Fifth Affiliated Hospital，Sun Yat-sen University from September 2013 to January 2014，so as to do the statistical analysis on the common cold and the Influenza alike occurred within half year after people taking the Vaccine.The results were divided into two groups.One was 6-35 months-old group，and the other was≥3 years-old.Then we did statistical analysis with SPSS19.0 software，and discussed the significance of differences between the immunological effects of these two kinds of vaccine.Result：For 6-35mouths-old group，the occurring frequency of common cold was 46.9% and 44.2% for imported and domestic vaccine separately，there was no statistically significant difference（P0.05），while 1.9% and 2.6% for influenza separately， there was no statistically significant difference（P0.05）.For≥3 years-old group，the frequency was 22.2% and 32.0% separately for common cold， there was no statistically significant difference（P0.05），while 1.8% and 1.3% for influenza，there was no statist