复方血栓通联合怡开治疗视网膜静脉栓塞的31例临床分析.DOC

复方血栓通胶囊联合复方樟柳碱联合治疗非增生性糖尿病视网膜病变的疗效分析 中国人民解放军454医院 眼科 徐晓红 彭琦 孙群林 蔡婷婷 通讯作者：彭琦 【摘要】 目的 探讨复方血栓通胶囊口服联合复方樟柳碱治疗糖尿病视网膜病变的疗效。 方法42例（42眼）非增生性糖尿病视网膜病变患者，予以复方血栓通胶囊1.5g 口服 3次/d 联合复方樟柳碱注射液2ml颞浅动脉旁注射，1次/d，进行2个疗程。疗程结束一个月后观察视力(VA)、视野平均光敏感度(MS)、视觉诱发电位(VEP) 的变化。 结果 经治疗后视力有提高趋势,视网膜光敏感度明显增加(P0．01)、VEP P100波潜伏期明显缩短(P0．01)、VEP P100波振幅明显提高(P0．01)。结论 复方血栓通胶囊联合复方樟柳碱药物治疗非增生性糖尿病视网膜病的疗效可靠，值得临床上进一步推广应用。 【关键词】非增生性糖尿病视网膜病变；复方血栓通胶囊；复方樟柳碱注射液；视力 视野 视觉诱发电位 Abstract:Objective To investigate the efficiency of the treatment of Non proliferative diabetic retinopathy combined with FuFang Xueshuantong capsule and FuFang ZhangLiuJianin injection . Methods 42 patients with Non proliferative diabetic retinopathy (42 eyes) were randomly assigned to 42 cases treated with FuFang Xueshuantong capsule united FuFang ZhangLiuJian injection. The patients were taken the FuFang Xueshuantong capsule through 1.5g, three times a day and FuFang ZhangLiuJian injection 2 ml , injected under skin around superficial temporal artery ,one time a day. after 2 courses of treatment. The visual acuity(VA)，mean defect(MD) visual evoked potential(VEP) were evaluated after a month . Result： there were in increasing mean sensitivity(P0．01)，in shortening P100 latency(P0．01)，in improving VEP amplitude (P0．01)of the DR patients．And there is a increasing trend in VA. Conclusion: FuFang Xueshuantong capsule united FuFang ZhangLiuJian jnjection have reliable efficacy of the treatment of non proliferative diabetic retinopathy , it is worth to further spread as the use of clinical. Key word: Non proliferative diabetic retinopathy; FuFang Xueshuantong capusla; FuFang ZhangLiuJian jnjection；The visual acuity; visual field VF; visual evoked potential 糖尿病视网膜病变(diabetic retinopathy，DR)是糖尿病的严重并发症之一，也是眼科主要的致盲性疾病。主要表现为破坏视网膜毛细血管，导致不同程度视力（visual acuity，VA)，视野（visual field VF)，视觉诱发电位(visual evoked potential VEP)的改变，包括视力下降（VA)，视野平均缺损（mean defect，MD）升高、VEP P100波潜伏期延长、VEP P100波振幅下降，如治疗不当可引起多种并发症，及时正确治疗是减少并发症，保护视功能的重要措施。DR临床分期常分为非增生性和增生性两类。目前