159例短暂性脑缺血发作患者早期预后及其的影响因素分析.docVIP

159例短暂性脑缺血发作患者早期预后及其的影响因素分析 　　[摘要] 目的 分析短暂性脑缺血发作患者的早期预后及其影响因素。方法 方便收集2013年3月―2015年10月该院收治的159例短暂性脑缺血发作（TIA）患者，以住院7 d为观察终点，7 d内是否进展为脑梗死分为梗死组和非梗死组，采用Pearson单因素分析与多元Logistic回归分析，分析两组间的相?P危险因素。 结果 ABCD2评分与TIA后发生脑梗死的比例成正相关，低危组15.1%，中危组31.5%，高危组84.8%。单因素分析示年龄、高血压、糖尿病、冠心病、颈动脉硬化斑块，高同型半胱氨酸血症为有统计学意义的影响因素。多元Logistic回归分析显示年龄、高血压、糖尿病、颈动脉硬化斑块为TIA进展至脑梗死的独立危险因素。结论 ABCD2评分高者TIA进展至脑梗死风险高。年龄、高血压、糖尿病、颈动脉硬化斑块为TIA进展至脑梗死的危险因素。 　　[关键词] TIA；脑梗死；预后；影响因素 　　[中图分类号] R743.31 [文献标识码] A [文章编号] 1674-0742（2017）03（b）-0060-03 　　[Abstract] Objective To analyze the early prognosis and influence factors of transient cerebral ischemia attack. Methods 159 cases of patients with TIA in our hospital from March 2013 to October 2015 were selected and divided into two groups whether the patients had cerebral infarction or not， and the related risk factors between groups were analyzed by the Pearson single-factor analysis and multi-Logistic regression analysis. Results The ABCD2 score was positively correlated with the incidence rate of cerebral infarction after TIA， which was respectively 15.1%， 31.5% and 84.8% in the low-risk group， middle-risk group and high-risk group， and the single-factor analysis showed that the age， hypertension， diabetes， coronary heart disease， carotid plaque， hyperhomocysteinemia were the influence factors with statistical significance， and the multi-Logistic regression analysis showed that the age， hypertension， diabetes and carotid plaque were the independent risk factors of TIA progressed to cerebral infarction. Conclusion The risk of TIA progressed to cerebral infarction in the patients whose ABCD2 is higher is high， and the age， hypertension， diabetes and carotid plaque are the independent risk factors of TIA progressed to cerebral infarction. 　　[Key words] TIA； Cerebral infarction； Prognosis； Influence factor 　　短暂性脑缺血发作（TransientIschemicAttack，TIA） 是脑梗死的先兆，TIA后卒中风险增高，可作为卒中的预警信号。然而TIA的风险因素和早期预后因人而异， 如何预测TIA后早期发生梗死的风险是临床医生和患者共同关注的焦点。该文旨在探讨该院2013年3月―2015年10月收治的159例TIA患者的危险因素