早期间歇CPAP治疗小儿重症肺炎的临床研究.docVIP

早期、间歇CPAP治疗小儿重症肺炎的临床研究 【摘要】 目的：探究早期、间歇持续气道正压通气（CPAP）治疗小儿重症肺炎的临床效果。方法：选取2015年8月-2016年8月在本院进行治疗的重症肺炎患儿120例，按随机数字表法分为两组，每组各60例。两组均进行抗感染、吸痰等常规治疗，对照组实施鼻塞式CPAP治疗，观察组采用鼻塞式CPAP和鼻导管给氧交替使用。对两组临床指标、血气指标、疗效及预后情况进行比较。结果：观察组住院时间、临床症状消失时间（呼吸困难、发绀、肺部??音）及心率恢复正常时?g较对照组明显减少，比较差异均有统计学意义（P0.05）。治疗后24 h，观察组氢离子浓度指数（pH）、血氧饱和度（SaO2）、动脉血二氧化碳分压（PaCO2）、动脉血氧分压（PaO2）指标较对照组明显改善，比较差异均有统计学意义（P0.05）。观察组不良反应发生率与对照组比较，差异无统计学意义（P0.05）。观察组病死率明显低于对照组，治疗效果明显升高，比较差异有统计学意义（P0.05）。结论：给予重症肺炎患儿早期、间歇CPAP治疗可改善患儿血气指标，缩短临床症状改善时间，提高治疗效果，促进患儿康复。 本文采集自网络，本站发布的论文均是优质论文，版权和著作权归原作者所有。 　【关键词】 早期； 间歇CPAP； 鼻导管； 小儿重症肺炎 　　【Abstract】 Objective：To investigate the clinical effect of early intermittent continuous positive airway pressure （CPAP） for the treatment of children with severe pneumonia.Method：120 children with severe pneumonia who had received treatment in our hospital from August 2015 to August 2016 were selected and randomly divided into two groups，60 cases in each group.They were all given the anti-infection and sputum suctioning conventional treatment.The control group was given nasal obstruction CPAP，while the observation group were given nasal catheter oxygen inhalation and nasal obstruction CPAP.The clinical indicators， blood gas indicators， efficacy and prognosis of two groups were compared.Result：The length of hospital stay，time for the disappearing of clinical symptoms （dyspnea， cyanosis， pulmonary rales） and time for the recovery of heart rate in observation group were significantly reduced compared with the control group，the differences were statistically significant（P0.05）.After treatment 24 h，concentration of hydrogen ion index（pH），oxygen saturation（SaO2），arterial partial pressure of carbon dioxide（PaCO2），and arterial partial pressure of oxygen （PaO2） in the observation group were significantly improved compared with the control group，the differences were statistically significant（P0.05）.There was no statistically significant difference in the incidence of adverse reactions of two groups（P0.05）.The morta