天麦消渴片及吡格列酮片两种的方案治疗2型糖尿病效价比分析.docVIP

天麦消渴片及吡格列酮片两种的方案治疗2型糖尿病效价比分析 　　[摘要] 目的 分析天麦消渴片及吡格列酮片两种方案治疗2型糖尿病效价比，以期为临床应用提供证据。方法 将2012年2月―2015年6月在该院门诊就诊的171例糖尿病患者，随机分为两组，治疗组 86例，对照组 85例， 两组予饮食控制、适当运动，治疗组给予天麦消渴片、对照组给予吡格列酮片，一个月为1个疗程，连续服用3个疗程。于治疗前后观察两组临床症状，检查血常规、空腹血糖、餐后血糖、糖化血红蛋白、肝肾功能及心电图，监测用药过程中药物相关不良反应。 结果 两组患者治疗3个疗程后进行临床疗效比较，治疗组86例中显效45例（52.3%），有效36例（41.9%），无效5例（5.8%），总有效率为94.2%；对照组85例中显效37例（43.5%），有效31例（36.5%），无效17例（20.0%），总有效率为80.0%。观察组总有效率明显高于对照组，P0.05。成本-效果分析显示治疗组单位治疗效果所花费用较对照组低0.73元。结论 天麦消渴片及吡格列酮片治疗2型糖尿病这两种方案中，天麦消渴片临床疗效高，成本低，是经济合理的药物。 　　[关键词] 天麦消渴片；吡格列酮片；2型糖尿病；效价比 　　[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062（2016）03（b）-0027-03 　　[Abstract] Objective To analyze the two schemes of Tianmaixiaoke tablets and pioglitazone tablets in treatment of type 2 diabetes which in order to provide evidence for clinical application. Methods From February 2012 to June 2015 ，171 cases of diabetic patients in outpatient department of our hospital， were randomly divided into for two groups， treatment group （86 cases） and control group （85 cases）. Two groups received diet control， proper exercise， the treatment group given Tianmaixiaoke tablets and control group were treated with pioglitazone tablets， a month for a course of treatment， continuous take three courses. An observation of the clinical symptoms of the two groups before and after treatment， blood routine examination， fasting blood glucose， postprandial blood glucose， glycosylated hemoglobin， liver and kidney function and ECG， monitoring the process of drug in drug related adverse reactions. Results After treatment of 3 courses of treatment， the two groups of patients were clinical efficacy compared treatment group（86 cases） in 45 cases were cured（52.3%）， effective in 36 cases （41.9%）， invalid in 5 cases （5.8%）. The total effective rate was 94.2%； control group （85 cases） markedly effective in 37 cases （43.5%）， effective in 31 cases （36.5%）， invalid in 17 cases （20.0%）. The total effective rate was 80.0%. The total effective rate of the observation group was signific