应用疫苗免疫防制猪瘟UsageofVaccineforthePreventionagainst.PDFVIP

應用疫苗免疫防制豬瘟 Vaccine Usage for Swine Fever Prevention 鍾明華 Dr. Ming-Hwa Jong 2016南京 2016 Nanjing 內 容 Contents  豬瘟及豬瘟病毒簡介 Swine fever and swine fever introduction  豬瘟C-strain, E2疫苗之特性 C-strain swine fever, E2 vaccine and its characteristics  豬瘟防制用之疫苗 Swine fever prevention vaccine  LPC細胞苗之安全性及效力 Safety and efficiency of LPC cellular vaccine 豬瘟Swine fever 豬瘟病毒對豬隻之傷害 Harm of Swine fever virus  免疫系統之破壞 Damage the immune system 淋巴細胞流失 Loss of lymphocytes 胸腺委縮 Thymus involution 成熟中性白血球減少 Decreases of mature neutrophil granulocytes 幼弱白血球出現於末梢血流 Immature white blood cells in capillary  血管內皮細胞之破壞 Vascular endothelial cell damage 出血、紫斑、血管內皮細胞增生 Bleeding, peliosis, vascular endothelial cell hyperplasia 豬瘟免疫學 Swine fever immunology  細胞性免疫角色重要 Important role of cellular immunity 消滅感染細胞及限制病毒擴散 Eliminates infected cells and limits the spread of virus 早期保護 Early stage protection  體液性抗體 Body fluid antibody 協助降低病毒擴散及排毒 Assists in eliminating the virus and detoxification 目前豬瘟防制用疫苗種類 Current Swine Fever Vaccine Types 兔化脾淋疫苗 Rabbit spleen vaccine 細胞培養疫苗 Cell culture vaccine 豬腎細胞, 幼兔腎細胞,羔羊腎細胞,天竺鼠腎細胞…… Swine nephrocyte, young rabbit nephrocyte, young sheep nephrocyte , guinea pig nephrocyte  E2標幟次單位疫苗 E2 flag subunit vaccine 兔化疫苗、細胞培養疫苗及 標幟次單位疫苗比較 Comparison between different types of vaccines 優點Advantage 缺點Disadvantage 兔化疫苗  利用家兔做為過濾器