2010年肿瘤临床进展课件.pptVIP

TROPIC：ORR / TTP MP (N=377) CBZP (N=378) HR (95%CI) P Tumor assessment RR *(%) 4.4 14.4 - 0.0005 mTTP (mos) 5.4 8.8 0.61(0.49-0.76) 0.0001 PSA assessment RR *(%) 17.8 39.2 - 0.0002 mTTP (mos) 3.1 6.4 0.75(0.63-0.90) 0.001 Pain assessment RR *(%) 7.8 9.2 - 0.6286 mTTP (mos) NR 11.1 0.91(0.69-1.19) 0.5192 ASCO 2010 - Sartor, AO, et al. abstract #4058. *Determined only for subjects with at baseline measurable disease, PSA≥20ng/ml, or pain, respectively TROPIC：主要不良事件 Adverse Event Grade ≥ 3, % Mitoxantrone + Prednisone(n = 371) Cabazitaxel + Prednisone(n = 371) Any 39.4 57.4 Febrile neutropeni