朱亮《药学导论》2药效学-zhuliang教学材料.pptVIP

药物效应动力学Pharmacodynamics;药物作用和药理学效应;ACh MR;治疗作用和不良反应(Therapeutic Effects and Adverse Reactions); ;;毒性反应 (Toxic reaction, Toxicity) 用量过大或过久对机体功能、形态产生损害。 药理作用延伸;苯巴比妥催眠 ? 次晨头晕、困倦;停药反应 (Withdrawal reaction) 突然停药后原有疾病加重 也称反跳 (Rebound reaction);继发反应（secondary rection）; 变态反应（Allergic rection）;特异质反应  （idiosyncrasy）;依赖性/成瘾性（dependence/addiction）;If something is not a poison, it is not a drug The dose makes the poison;;药物的量效关系 Dose-effect Relationship;量效曲线（Dose response curve）;相关概念;Potency: a measure of the amount of drug necessary to produce an effect of a giv