生物化学讲义Chapter 26 (complete) RNA Metabolism教学案例.pptVIP

The 18S, 5.8S, and 28S rRNAs in eukaryotic cells are derived from one pre-rRNA molecule (the processing needs small nucleolar RNA-containing proteins). 25. Primary tRNA transcripts undergo a series of posttranscriptional processing The extra sequences at the 5` and 3` ends are removed by RNase P and RNase D respectively. The RNA in RNaseP is catalytic (Altman, 1983) Type IV introns are occasionally present in pre-tRNAs in eukaryotic cells. The CCA sequence is generated at the 3` end by the action of tRNA nucleotidyltransferase (having three active sites for the three ribonucleotides added)