直肠癌术后盆腔三维适形放疗的应用效果观察.docVIP

直肠癌术后盆腔三维适形放疗的应用效果观察 　　摘要：目的：观察采用盆腔三维适形放疗技术治疗的临床效果，为直肠癌术后的放疗方法选择提供参考。方法：将46例直肠癌患者手术后的放疗分成A，B俩组各23例，治疗时间均为3-6个周期，其中A组采用盆腔三维适形技术进行放射治疗，B组采用传统的盆腔调强方法进行放疗，并在手术后2年内对2组患者的治疗效果进行跟踪与观察。结果：放疗靶区剂量均匀性方面三维适形放疗方法方面明显好于调强放疗方法；根据WHO的疗效判定标准，至2013年10月15日截止对46例直肠癌患者术后放疗效果进行随访：A组完全缓解8例，占34.8%；部分缓解10例,占43.5%；稳定16例，占69.5%；进展例3例,占13.1%，治疗有效率为78.3%，一年生存率82.6%。B组完全缓解5例，占21.7%；部分缓解7例,占30.5%；稳定11例，占47.8%；进展例8例,占34.7%，治疗有效率为52.2%，一年生存率56.5%。俩组均未出现白细胞数量降低和肝、肾功能降低等放疗并发症。结论：盆腔三维适形放疗技术对放疗剂量的均匀性控制优势明显，稳定性、症状缓解率和一年生存率高，术复发率低，直肠癌患者手术后宜采用盆腔三维适形方法进行放射治疗。 　　关键词：直肠癌，三维适形放疗，盆腔 　　Abstract：ObjectiveObserve the pelvic three-dimensional conformal radiotherapy technology the clinical effect of treatment, postoperative radiotherapy for rectal cancer method choice to provide the reference.Methods The radiation treatment of 46 cases of rectal cancer patients after surgery can be divided into A, B two groups all the 23 cases, treatment time were 3 to 6 cycles, in which A group USES the pelvic technology of three dimensional conformal radiation therapy, group B with traditional methods of pelvic intensity-modulated radiation therapy, and the 2 years after surgery for tracking and observing the curative effect of two groups patients. Results Radiotherapy target dose uniformity in terms of three dimensional conformal radiation therapy in intensity modulated radiation therapy (imrt) is much better than method; According to the outcome of the world health organization (WHO) standards, on October 15, 2013 as of 46 cases of colorectal cancer patients with postoperative radiotherapy effect follow-up: A set of complete remission, 8 cases, accounting for 34.8%; Partial in 10 cases (43.5%), Stability in 16 cases, accounted for 69.5%; Progress in 3 cases, accounted for 13.1%, effective rate of 78.3%, a year survival rate was 82.6%. Group B complete remission in 5 cases, accounting for 21.7%; Partial in 7 cases, accounting for 30.5%; Stability in 11 cases, accounting for 47.8%; Progress in 8 cases, accounted for 34.7%, ef